Carl C, Engelhardt W, Teichmann G, Fuchs G
Department of Psychiatry, University of Würzburg, FRG.
Pharmacopsychiatry. 1988 Nov;21(6):432-3. doi: 10.1055/s-2007-1017040.
Isoflurane is the only routine volatile anesthetic which leads to a burst-suppression EEG in nontoxic concentrations and for which no memory impairments can be expected subsequent to anesthesia. After electrically induced spike-wave activity in electroconvulsive therapy (ECT), a brief period of a very flat EEG can be observed. This phenomenon may be closely related to the therapeutic effects of ECT. The results which have been achieved up to now in comparing ECT to anesthetic therapy with isoflurane, without seizures being induced, are presented.
异氟烷是唯一一种在无毒浓度下可导致爆发抑制脑电图的常规挥发性麻醉剂，且预计麻醉后不会出现记忆障碍。在电休克治疗（ECT）中电诱导产生棘波-慢波活动后，可观察到脑电图出现一段短暂的极平状态。这种现象可能与ECT的治疗效果密切相关。本文介绍了目前在不诱发癫痫发作的情况下，将ECT与异氟烷麻醉治疗进行比较所取得的结果。
