Second Department of Internal Medicine, Osaka Medical College, Japan.
Division of Neurology, Forth Department of Internal Medicine, Osaka Medical College, Japan.
Intern Med. 2020 Sep 1;59(17):2113-2116. doi: 10.2169/internalmedicine.4684-20. Epub 2020 May 23.
A 68-year-old woman presented with a 2-year history of worsening unsteady gait. Her neurological examination revealed peripheral neuropathy with lower limb sensory dominance. T2-weighted imaging revealed a disorder of the posterior cervical cord. Blood test findings revealed vitamin B deficiency, and gastroscopy revealed typical findings of autoimmune gastritis. She received vitamin B supplementation, but some peripheral neuropathy symptoms persisted due to longstanding vitamin B deficiency. Asymptomatic patients should undergo gastroscopy to detect autoimmune gastritis, as chronic vitamin B deficiency causes irreversible peripheral neuropathy.
一位 68 岁女性因进行性加重的不稳步态就诊,病史 2 年。神经系统检查发现下肢感觉占优势的周围神经病。T2 加权成像显示颈髓后部紊乱。血液检查结果显示维生素 B 缺乏,胃镜检查显示自身免疫性胃炎的典型表现。她接受了维生素 B 补充治疗,但由于长期维生素 B 缺乏,一些周围神经病症状仍然存在。无症状患者应行胃镜检查以发现自身免疫性胃炎,因为慢性维生素 B 缺乏可导致不可逆的周围神经病。