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Sufficient increment of sulfonylurea without reintroduction of insulin ameliorates pubertal deterioration of glycaemic control in KCNJ11 neonatal diabetes treated with long-term sulfonylurea.

作者信息

Suzuki Shigeru, Mukai Tokuo, Kokumai Takahide, Furuya Akiko, Tanahashi Yusuke, Azuma Hiroshi

机构信息

Department of Pediatrics, Asahikawa Medical University, 2-1-1-1 Midorigaoka Higashi, Asahikawa, Hokkaido, 078-8510, Japan.

Department of Pediatrics, Japanese Red Cross Asahikawa Hospital, Asahikawa, Hokkaido, Japan.

出版信息

Diabetologia. 2020 Aug;63(8):1659-1661. doi: 10.1007/s00125-020-05182-9. Epub 2020 May 24.

DOI:10.1007/s00125-020-05182-9
PMID:32448915
Abstract
摘要

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Sufficient increment of sulfonylurea without reintroduction of insulin ameliorates pubertal deterioration of glycaemic control in KCNJ11 neonatal diabetes treated with long-term sulfonylurea.在长期使用磺脲类药物治疗的KCNJ11型新生儿糖尿病中,磺脲类药物足量增加而无需重新引入胰岛素可改善青春期血糖控制的恶化情况。
Diabetologia. 2020 Aug;63(8):1659-1661. doi: 10.1007/s00125-020-05182-9. Epub 2020 May 24.
2
Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study.KCNJ11 基因突变致新生儿糖尿病患者磺脲类药物长期治疗的有效性和安全性:一项国际队列研究。
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3
Sulfonylurea treatment outweighs insulin therapy in short-term metabolic control of patients with permanent neonatal diabetes mellitus due to activating mutations of the KCNJ11 (KIR6.2) gene.对于因KCNJ11(KIR6.2)基因激活突变导致的永久性新生儿糖尿病患者,在短期代谢控制方面,磺脲类药物治疗优于胰岛素治疗。
Diabetologia. 2006 Sep;49(9):2210-3. doi: 10.1007/s00125-006-0329-x. Epub 2006 Jul 1.
4
Successful transition from insulin to sulfonylurea therapy in a patient with monogenic neonatal diabetes owing to a KCNJ11 F333L [corrected] mutation.一名因KCNJ11 F333L[已修正]突变导致单基因新生儿糖尿病的患者成功从胰岛素治疗过渡到磺脲类药物治疗。
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Successful sulfonylurea treatment of a neonate with neonatal diabetes mellitus due to a new KCNJ11 mutation.成功用磺酰脲类药物治疗因 KCNJ11 新突变导致的新生儿糖尿病的新生儿。
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Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes.KCNJ11型新生儿糖尿病成功转换为使用磺脲类药物治疗取决于突变情况和糖尿病病程。
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Permanent neonatal diabetes by a new mutation in KCNJ11: unsuccessful switch to sulfonylurea.由KCNJ11基因新突变导致的永久性新生儿糖尿病:磺脲类药物转换治疗失败。
Arch Endocrinol Metab. 2015 Dec;59(6):559-61. doi: 10.1590/2359-3997000000076. Epub 2015 Aug 28.

引用本文的文献

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J Diabetes Investig. 2024 Dec;15(12):1711-1724. doi: 10.1111/jdi.14312. Epub 2024 Sep 30.

本文引用的文献

1
Precision Medicine: Long-Term Treatment with Sulfonylureas in Patients with Neonatal Diabetes Due to KCNJ11 Mutations.精准医学:KCNJ11 基因突变致新生儿糖尿病患者的磺脲类药物长期治疗。
Curr Diab Rep. 2019 Jun 27;19(8):52. doi: 10.1007/s11892-019-1175-9.
2
Usefulness of antidiabetic alpha-glucosidase inhibitors: a review on the timing of administration and effects on gut hormones.抗糖尿病 α-葡萄糖苷酶抑制剂的作用:给药时间和对肠道激素影响的综述。
Endocr J. 2019 May 28;66(5):395-401. doi: 10.1507/endocrj.EJ19-0041. Epub 2019 Apr 23.
3
Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study.
KCNJ11 基因突变致新生儿糖尿病患者磺脲类药物长期治疗的有效性和安全性:一项国际队列研究。
Lancet Diabetes Endocrinol. 2018 Aug;6(8):637-646. doi: 10.1016/S2213-8587(18)30106-2. Epub 2018 Jun 4.
4
Hypoglycemia in sulfonylurea-treated KCNJ11-neonatal diabetes: Mild-moderate symptomatic episodes occur infrequently but none involving unconsciousness or seizures.磺酰脲类药物治疗的 KCNJ11 新生儿糖尿病中的低血糖:轻度-中度有症状发作不常见,但无无意识或癫痫发作。
Pediatr Diabetes. 2018 May;19(3):393-397. doi: 10.1111/pedi.12599. Epub 2017 Dec 5.
5
Psychosocial factors are associated with metabolic control in adolescents: research from the Hvidoere Study Group on Childhood Diabetes.社会心理因素与青少年的代谢控制相关:来自赫维多勒儿童糖尿病研究小组的研究
Pediatr Diabetes. 2009 Dec;10 Suppl 13:9-14. doi: 10.1111/j.1399-5448.2009.00609.x.
6
Pubertal transitions in health.青春期健康过渡。
Lancet. 2007 Mar 31;369(9567):1130-9. doi: 10.1016/S0140-6736(07)60366-3.
7
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.因Kir6.2突变导致糖尿病的患者从胰岛素转换为口服磺脲类药物治疗。
N Engl J Med. 2006 Aug 3;355(5):467-77. doi: 10.1056/NEJMoa061759.
8
Insulin resistance during puberty: results from clamp studies in 357 children.青春期胰岛素抵抗:357名儿童钳夹试验的结果
Diabetes. 1999 Oct;48(10):2039-44. doi: 10.2337/diabetes.48.10.2039.