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直肠阴道手术后瘘:谁真正受益于造口术?

Post surgical rectovaginal fistula: who really benefits from stoma diversion?

机构信息

Department of Surgery, IRCCS, Ospedale Sacro Cuore Don Calabria, Via Don A. Sempreboni 5, Negrar Di Valpolicella, 37024, Verona, Italy.

Departement of Surgery, "San Pellegrino" Hospital, Castiglione delle Stiviere, Mantova, Italy.

出版信息

Updates Surg. 2021 Feb;73(1):165-171. doi: 10.1007/s13304-020-00810-w. Epub 2020 May 24.

Abstract

To analyze the role of stoma diversion and timing of stoma maintenance in the healing of post-surgical Recto Vaginal Fistulae (psRVF). A retrospective analysis of a prospectively maintained registry. All patients with a psRVF diagnosed at IRCCS Sacro Cuore-Don Calabria Hospital of Negrar di Valpolicella from January 2002 to December 2016 were analyzed. The baseline treatment was a fecal diversion. Patients were divided into two groups according to healing time: < 6 months (Group 1) or > 6 months (Group 2). 2043 women underwent rectal resections in the study period. We recorded 37 patients with psRVF (1.8%). Nineteen women (51.3%) healed (Group 1) within 6 months. The median time of psRVF recovery in group 1 was 99.7 days. Concomitant local treatment of the fistula did not influence the healing rate (p 0.8). Colostomies were significantly higher in group 1 (p 0.003). The size of the psRVF influenced the success rate of fistula healing with loop stoma (p 0.07). A multivariate analysis the presence of fever and pelvic abscess (pelvis sepsis) were significantly associated with diversion failure (p 0.035). A step-up approach with the maintenance of loop stoma at least for six months for all patients with psRVF could be changed. Patients with larger fistula and pelvic sepsis at index procedure should be addressed earlier to a specific second-level treatment.

摘要

分析造口转流术和造口维持时机对直肠阴道瘘(RVF)术后愈合的作用。对前瞻性维护的注册中心进行回顾性分析。分析 2002 年 1 月至 2016 年 12 月期间在意大利里乔内 Sacro Cuore-Don Calabria 医院诊断为 RVF 的所有患者。最初治疗为粪便转流。根据愈合时间将患者分为两组:<6 个月(第 1 组)或>6 个月(第 2 组)。研究期间,2043 名女性接受了直肠切除术。我们记录了 37 例 RVF 患者(1.8%)。19 名女性(51.3%)在 6 个月内愈合(第 1 组)。第 1 组 RVF 恢复的中位数时间为 99.7 天。瘘管的局部联合治疗并未影响愈合率(p>0.8)。第 1 组的结肠造口术明显更高(p<0.003)。RVF 的大小影响 Loop 造口术治疗瘘管愈合的成功率(p=0.07)。多变量分析显示,发热和骨盆脓肿(骨盆脓毒症)与转流失败显著相关(p=0.035)。对于所有 RVF 患者,采用至少维持 Loop 造口术 6 个月的递进治疗方法可能会发生改变。对于指数手术中存在较大瘘管和骨盆脓毒症的患者,应尽早进行特定的二级治疗。

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