Tactus Addiction Treatment, Enschede, The Netherlands.
Nijmegen Institute for Scientist-Practitioners in Addiction, Nijmegen, The Netherlands.
Eat Weight Disord. 2021 Apr;26(3):911-919. doi: 10.1007/s40519-020-00929-0. Epub 2020 May 24.
To evaluate the long-term effectiveness of a web-based therapist-delivered cognitive behavioral therapy (CBT) for patients with eating disorders (ED).
We used follow-up data from a randomized controlled trial that evaluated a web-based CBT on ED psychopathology and related health, compared to a waiting list control (WL) condition. As participants of the WL condition started the intervention after their waiting period, follow-up data included participants from both groups. The primary outcome was change from baseline, at 3, 6, and 12-month intervals in ED psychopathology, analyzed using mixed models for repeated measures. Secondary outcomes included body dissatisfaction, BMI, physical health, mental health, self-esteem, quality of life, and social functioning.
The population comprised 212 participants in total, in three subgroups: bulimia nervosa (BN; n = 44), binge eating disorder (BED; n = 83), and ED not otherwise specified (EDNOS; n = 85). Treatment effects were sustained during follow-up, with generally large effect sizes for the reduction of ED psychopathology and body dissatisfaction, and small to moderate effect sizes for physical and mental health, self-esteem, social functioning, and quality of life. Most effects were found for all three subgroups, except for long-term improvements in self-esteem and quality of life among participants with BN and EDNOS.
This study showed long-term sustainability of treatment effects up to 1-year post-treatment of a web-based therapist-delivered CBT for patients with various ED.
Level IV, evidence obtained from multiple time series analysis, with intervention.
NTR2415-Dutch Trial Registry ( http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2415 ).
评估基于网络的治疗师提供的认知行为疗法（CBT）治疗饮食障碍（ED）患者的长期疗效。
我们使用了一项随机对照试验的随访数据，该试验评估了一种基于网络的 CBT 对 ED 精神病理学及相关健康的影响，与等待名单对照（WL）条件相比。由于 WL 条件下的参与者在等待期后开始干预，因此随访数据包括来自两组的参与者。主要结果是 ED 精神病理学在基线、3、6 和 12 个月时的变化，使用重复测量混合模型进行分析。次要结果包括身体不满、BMI、身体健康、心理健康、自尊、生活质量和社会功能。
总人口共有 212 名参与者，分为三个亚组：神经性贪食症（BN；n=44）、暴食障碍（BED；n=83）和未特定的 ED（EDNOS；n=85）。在随访期间，治疗效果持续存在，ED 精神病理学和身体不满的减少效果通常较大，身体健康、心理健康、自尊、社会功能和生活质量的减少效果较小到中等。大多数效果在所有三个亚组中都有发现，除了 BN 和 EDNOS 患者的自尊和生活质量的长期改善。
本研究表明，基于网络的治疗师提供的 CBT 治疗各种 ED 患者，治疗效果在治疗后 1 年内可持续。
四级，干预后从多个时间序列分析中获得的证据。
NTR2415-荷兰试验登记处（http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2415）。
