Section of Eating Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
South London and Maudsley NHS Foundation Trust, Maudsley Hospital, London, UK.
Int J Eat Disord. 2020 Sep;53(9):1377-1399. doi: 10.1002/eat.23299. Epub 2020 May 25.
Research suggests that a variety of biological and psychosocial factors are associated with the sexual health of women diagnosed with anorexia nervosa (AN). This systematic scoping review, conducted in accordance to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines, synthesizes the current literature concerning sexual function and dysfunction in women with AN.
We searched PubMed, EMBASE, and PsychInfo for literature published until April 2020. All study designs were eligible for inclusion, providing they focused on sexual function and dysfunction in women with AN. Studies that only included outcomes related to gender identity or sexual orientation were excluded.
N = 28 studies met criteria for inclusion in the review. All studies were conducted in Western countries and the majority employed either a cohort or cross-sectional design. Although measures of sexual function and dysfunction varied markedly across studies, most studies adopted a biopsychosocial framework. Libido may be linked to body mass index (BMI), while other aspects of sexual functioning and behavior might not be specifically associated with weight status. Limited data are available on evidence-based interventions.
Sexual dysfunction in women with AN is common. Although some of the variance is explained by low BMI, associated physiological sequelae and other psychosocial factors are also involved. Sexual dysfunction is a relevant clinical problem and clinicians should sensitively incorporate questions related to sexual function into their eating disorder assessments. Future research, using more robust designs and validated outcome measures, is needed to better understand causal pathways between the biological and psychosocial correlates of AN and sexual dysfunction. Identifying predictors of sexual function and dysfunction in more diverse groups of people with AN will support the development of evidence-based therapies.
研究表明,多种生物学和心理社会因素与被诊断患有神经性厌食症(AN)的女性的性健康有关。本系统范围综述按照系统评价和荟萃分析报告的首选项目进行,综合了目前关于 AN 女性性功能障碍的文献。
我们在 PubMed、EMBASE 和 PsychInfo 上搜索了截至 2020 年 4 月发表的文献。所有研究设计都符合纳入标准,只要它们专注于 AN 女性的性功能和性功能障碍。仅包括与性别认同或性取向相关结果的研究被排除在外。
N=28 项研究符合纳入本综述的标准。所有研究均在西方国家进行,大多数采用队列或横断面设计。尽管性功能和性功能障碍的测量方法在研究中差异很大,但大多数研究采用了生物心理社会框架。性欲可能与体重指数(BMI)有关,而其他方面的性功能和行为可能与体重状况没有特定关联。关于基于证据的干预措施的数据有限。
AN 女性的性功能障碍很常见。尽管一些变异可以用低 BMI 来解释,但相关的生理后果和其他心理社会因素也参与其中。性功能障碍是一个相关的临床问题,临床医生应在对饮食失调的评估中敏感地纳入与性功能相关的问题。需要使用更稳健的设计和经过验证的结果测量来进行未来的研究,以更好地理解 AN 与性功能障碍的生物学和心理社会相关因素之间的因果关系。在更多患有 AN 的不同人群中确定性功能和性功能障碍的预测因素,将支持基于证据的治疗方法的发展。