利用光相干断层扫描评估颞下颌关节紊乱中的神经退行性和炎症过程。
Evaluation of neurodegenerative and inflammatory processes in temporomandibular joint disorders using optical coherence tomography.
机构信息
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Adıyaman University, Adiyaman, Turkey.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mersin University, Mersin, Turkey.
出版信息
J Stomatol Oral Maxillofac Surg. 2021 Apr;122(2):151-155. doi: 10.1016/j.jormas.2020.05.014. Epub 2020 May 23.
INTRODUCTION
Temporomandibular joint disorders (TMD) is a process with systemic effects rather than local effects. The purpose of this study is to examine the retinal layer structure using optical coherence tomography (OCT) method in order to detect possible degenerative and inflammatory process in patients with TMD.
MATERIAL AND METHODS
Thirty-five healthy controls and 34TMD patients were evaluated bilaterally in this study. The retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and choroidal thickness were analyzed using OCT.
RESULTS
When TMD patients were compared with healthy controls, GCL and IPL volumes and RNFL thickness decreased; while choroidal thickness increased. In the unilateral TMD patients, there was no statistically significant difference in GCL, IPL, RNFL and choroidal thickness between the affected and the unaffected regions.
DISCUSSION
OCT findings showed GCL and IPL volumes and RNFL thickness were decreased while choroidal thickness was increased in TMD patients. These findings suggest that TMD may cause neurodegeneration and inflammation.
简介
颞下颌关节紊乱（TMD）是一个具有全身效应而非局部效应的过程。本研究旨在使用光学相干断层扫描（OCT）方法检查视网膜层结构，以检测 TMD 患者可能存在的退行性和炎症过程。
材料与方法
本研究共评估了 35 名健康对照者和 34 名 TMD 患者的双侧。使用 OCT 分析视网膜神经纤维层（RNFL）、神经节细胞层（GCL）、内丛状层（IPL）和脉络膜厚度。
结果
与健康对照组相比，TMD 患者的 GCL 和 IPL 体积以及 RNFL 厚度减小，而脉络膜厚度增加。在单侧 TMD 患者中，受累侧和未受累侧的 GCL、IPL、RNFL 和脉络膜厚度之间无统计学差异。
讨论
OCT 结果显示 TMD 患者的 GCL 和 IPL 体积以及 RNFL 厚度减小，脉络膜厚度增加。这些发现表明 TMD 可能导致神经退行性变和炎症。
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