Department of Otorhinolaryngology, Plastic Head and Neck Surgery, Kliniken Maria Hilf, Viersener Str. 450, 41063, Mönchengladbach, Germany.
Aristotle University of Thessaloniki, Thessaloniki, Greece.
Eur Arch Otorhinolaryngol. 2020 Nov;277(11):3169-3177. doi: 10.1007/s00405-020-06080-x. Epub 2020 May 25.
To evaluate, whether the regional variability of tonsil surgery in terms of the 16 Federal States of Germany was mirrored by a comparable variability of bleeding complications in male and female patients.
A longitudinal population-based inpatient cohort study was performed including all patients who had undergone tonsil surgery between 2005 and 2018. The database was provided by the Federal Statistical Office of Germany and included all inpatient cases after tonsillectomy (with or without adenoidectomy), tonsillotomy, abscess-tonsillectomy and secondary tonsillectomy. The population was stratified by region (16 Federal States) and gender. Operation rates were calculated in relation to the end-year population number of each region. Bleeding percentages were calculated for each calendar year and region as the number of procedures to achieve hemostasis divided by the total number of operations.
The surgical rates varied significantly between the 16 Federal States in male, female and all patients (p = 0.001). Revision surgery to achieve hemostasis was predominantly performed in male patients (5.2-11.4% male vs. 3.7-7.6% female patients). Bleeding percentages did not differ significantly from national values in male and female patients in 5 Federal States, but were significantly higher than the national average in 3 Federal States and significantly lower in 7 Federal States for both genders (p < 0.05), while in 1 Federal State it was significantly lower only for the male patients. Pearson's correlation coefficient for surgical and bleeding rates was positive and statistically significant (p < 0.05) for all Federal States, except for two. This phenomenon was emphasized by female gender.
Gender had an impact not only on surgical rates but also on bleeding percentages and this was independent from the decrease in the total number of operations. Surprisingly, there was a clear correlation between the rates of both variables in the majority of the Federal States of Germany. It needs further studies to clarify, why a higher prevalence of surgical practice, thus surgical experience, was not followed by lower bleeding complications.
评估德国 16 个联邦州在扁桃体手术方面的地域差异是否反映在男女患者出血并发症的可比变异性上。
进行了一项基于人群的纵向住院患者队列研究,纳入了 2005 年至 2018 年间接受扁桃体手术的所有患者。数据库由德国联邦统计局提供,包括所有扁桃体切除术(伴或不伴腺样体切除术)、扁桃体切开术、脓肿扁桃体切除术和继发性扁桃体切除术的住院病例。人群按地区(16 个联邦州)和性别分层。手术率按每个地区的年末人口数计算。每年和每个地区的出血百分比按实现止血的手术次数除以总手术次数计算。
男性、女性和所有患者的手术率在 16 个联邦州之间差异显著(p=0.001)。为实现止血而进行的修正手术主要在男性患者中进行(5.2-11.4%男性与 3.7-7.6%女性患者)。在 5 个联邦州,男性和女性患者的出血百分比与全国平均值无显著差异,但在 3 个联邦州显著高于全国平均值,在 7 个联邦州男女患者的出血百分比均显著低于全国平均值(p<0.05),而在 1 个联邦州仅男性患者显著低于全国平均值。除了两个联邦州外,所有联邦州的手术率和出血率的 Pearson 相关系数均为正且具有统计学意义(p<0.05)。这种现象在女性中更为明显。
性别不仅对手术率有影响,而且对出血百分比有影响,而且这种影响独立于手术总数的减少。令人惊讶的是,德国大多数联邦州的这两个变量的比率之间存在明显的相关性。需要进一步的研究来阐明为什么手术实践的高患病率,即手术经验,没有带来更低的出血并发症。