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处于精神病高危状态个体的认知洞察力:一项荟萃分析。

Cognitive insight in individuals with an at-risk mental state for psychosis: A meta-analysis.

机构信息

INSERM, U1028; CNRS, UMR5292; Lyon Neuroscience Research Center, Psychiatric Disorders: from Resistance to Response, PSYR2 Team, Lyon, France.

University Lyon 1, Villeurbanne, France.

出版信息

Early Interv Psychiatry. 2021 Jun;15(3):449-456. doi: 10.1111/eip.12993. Epub 2020 May 26.

Abstract

AIM

To compare cognitive insight abilities measured with the Beck Cognitive Insight Scale (BCIS) between individuals with an at-risk mental state (ARMS) and healthy controls.

METHOD

Review and meta-analysis based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

RESULTS

A search for articles investigating cognitive insight in ARMS in the MEDLINE and ScienceDirect databases revealed five studies including 303 ARMS and 376 controls. Regarding BCIS subscales, ARMS individuals displayed significant higher scores for self-certainty than controls with a small-to-moderate effect size (ESg = 0.45 [0.23;0.67], P < .005), whereas no significant difference was observed for self-reflectiveness (ESg = -0.56 [-0.18;1.29], P = .14). No significant differences were observed between ARMS and controls for overall cognitive insight abilities as indexed by the BCIS composite score (ESg = -0.24 [-0.43;0.91], P = .45).

CONCLUSIONS

Self-certainty abnormalities seem to predate the expression of full-blown psychotic episode and to be higher in ARMS than in healthy controls. By contrast, ARMS did not display abnormal self-reflectiveness and overall cognitive insight abilities.

摘要

目的

比较贝克认知洞察力量表(BCIS)测量的处于精神病高危状态(ARMS)个体与健康对照者的认知洞察力能力。

方法

基于系统评价和荟萃分析的首选报告项目(PRISMA)指南进行综述和荟萃分析。

结果

在 MEDLINE 和 ScienceDirect 数据库中搜索调查 ARMS 认知洞察力的文章,共发现五项研究,包括 303 名 ARMS 患者和 376 名对照者。关于 BCIS 分量表,ARMS 个体的自我确信得分明显高于对照组,具有小到中等的效应量(ESg = 0.45 [0.23;0.67],P < .005),而自我反思方面则没有显著差异(ESg = -0.56 [-0.18;1.29],P =.14)。BCIS 综合评分指数的整体认知洞察力能力方面,ARMS 与对照组之间无显著差异(ESg = -0.24 [-0.43;0.91],P =.45)。

结论

自我确信异常似乎先于全面精神病发作的出现,且在 ARMS 中比在健康对照中更高。相比之下,ARMS 并未表现出异常的自我反思和整体认知洞察力能力。

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