[Dopamine metabolism and the GABA level in the structures of the nigrostriatal and mesolimbic systems of the rat brain in experimental pathology of higher nervous activity].

In population of outbred white rats there are individuals predisposed and unpredisposed to development of nonadaptive reactions of inhibitory type during elaboration of unilateral avoidance reflex in conditions of time deficit. Animals with weak adaptive processes are characterized by lowered levels of dopamine and dioxyphenilacetic acid in the striatum, of dopamine in Substantia nigra, of homovanillic acid in the n. accumbens and olfactory tubercle and of GABA--in the striatum, in comparison with the animals which did not show behavioural pathology.