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[大鼠在形成和执行不同复杂程度的条件性回避反应过程中黑质-纹状体系统中的多巴胺浓度]

[Dopamine concentration in the nigro-striatal system during elaboration and performance of conditioned avoidance reactions of various complexity in rats].

作者信息

Saul'skaia N B

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1981 Jun;67(6):797-803.

PMID:7274479
Abstract

Experiments in rats revealed that complication of the avoidance conditioning induced a concomitant increase of the dopamine content in the striatum. The dopamine content changes were biphasic in the subst. nigra; its increase in the unilateral avoidance shifted to a decrease in the bilateral avoidance conditioning. Actualization of both simple and complicated avoidance responses was followed by a similar increase of the dopamine content in the striatum.

摘要

对大鼠的实验表明,回避条件反射的并发症会导致纹状体中多巴胺含量随之增加。黑质中的多巴胺含量变化呈双相性;单侧回避时其含量增加,而双侧回避条件反射时则转为减少。简单和复杂回避反应的实现都会使纹状体中多巴胺含量出现类似的增加。

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