Kovács Katalin, Pakot Levente
Népességtudományi Kutatóintézet,Központi Statisztikai Hivatal Budapest, Buday László u. 1-3., 1024.
Magatartástudományi Intézet,Semmelweis Egyetem Budapest.
Orv Hetil. 2020 Jun;161(23):962-970. doi: 10.1556/650.2020.31725.
In recent years, a significant mortality peak has been observed several times during the first months in Hungary. So far, no mortality study clarified the connection between the mortality peaks and influenza with results comparable with findings from other countries.
Calculation of the influenza-related number of death and excess mortality rates in Hungary for the period between 2009/10 and 2016/17, using the statistical package FluMONO.
We applied the FluMOMO methods, a multivariable time series model with all-cause mortality as outcome, and with influenza-activity and extreme temperature as explanatory variables adjusting for time trend and seasonality. As an indicator of weekly influenza-activity (IA), we used the percentage of consultations for influenza-like illness (ILI) in general practices.
According to our estimation, 1091, 2969, 4036, 2336, 2608, 6470, 51 and 5162 deaths were attributable to influenza epidemics in the 2009/10, 2010/11, 2011/12, 2012/13, 2013/14, 2014/15, 2015/16 and 2016/17 seasons, respectively. The average annual mortality excess rate per 100,000 inhabitants ranged between 0.5 and 52.7. These results are similar to those from other countries regarding their order of magnitude. The Hungarian extra mortality, however, tends to be higher than that in countries with higher vaccination rates.
Influenza-related mortality tends to be lower in countries with higher vaccination rates. Increase in vaccination rates seems to be necessary in Hungary. Orv Hetil. 2020; 161(23): 962-970.
近年来,匈牙利在最初几个月内多次出现显著的死亡高峰。到目前为止,尚无死亡率研究能阐明这些死亡高峰与流感之间的联系,其结果也无法与其他国家的研究结果相媲美。
使用统计软件FluMONO计算2009/10至2016/17期间匈牙利与流感相关的死亡人数和超额死亡率。
我们应用了FluMOMO方法,这是一种以全因死亡率为结果,以流感活动和极端温度为解释变量,并对时间趋势和季节性进行调整的多变量时间序列模型。作为每周流感活动(IA)的指标,我们使用了全科医疗中流感样疾病(ILI)咨询的百分比。
根据我们的估计,在2009/10、2010/11、2011/12、2012/13、2013/14、2014/15、2015/16和2016/17季节,分别有1091、2969、4036、2336、2608、6470、51和5162例死亡可归因于流感流行。每10万居民的年平均超额死亡率在0.5至52.7之间。这些结果在数量级上与其他国家的结果相似。然而,匈牙利的额外死亡率往往高于疫苗接种率较高的国家。
疫苗接种率较高的国家中,与流感相关的死亡率往往较低。匈牙利似乎有必要提高疫苗接种率。《匈牙利医学周报》。2020年;161(23):962 - 970。