Elimination from rat circulation of goat and sheep haptoglobin and their complexes with rat haemoglobin.

The rate of elimination from rat circulation of 125I-labelled human, goat and sheep haptoglobin, and their complexes with rat haemoglobin was studied. The clearance of human haptoglobin-rat haemoglobin complex from rat circulation was about 5 times faster than that of free haptoglobin. For sheep and goat haptoglobin and their complexes with rat haemoglobin the rate of elimination was identical, the half-life time t 1/2 ranging from 8 to 9 h.