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妊娠期新型冠状病毒肺炎的并发症与结局:证据何在?

Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence?

作者信息

Teles Abrao Trad Ayssa, Ibirogba Eniola R, Elrefaei Amro, Narang Kavita, Tonni Gabriele, Picone Olivier, Suy Anna, Carreras Moratonas Elena, Kilby Mark D, Ruano Rodrigo

机构信息

Maternal-Fetal Medicine Division, Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine , Rochester, MN, USA.

Prenatal Diagnostic Unit, Department of Obstetrics and Gynaecology, AUSL Istituto Di Ricerca a Carattere Clinico Scientifico (IRCCS) Di Reggio Emilia , Reggio Emilia, Italy.

出版信息

Hypertens Pregnancy. 2020 Aug;39(3):361-369. doi: 10.1080/10641955.2020.1769645. Epub 2020 May 26.

Abstract

OBJECTIVES

To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes.

METHODS

A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SARS-CoV-2 infection at any time during their pregnancy were reviewed and summarized .

RESULTS

We summarized the outcomes of a total of 155 pregnant women and 118 neonates. The evidence suggests a similar rate of severe COVID-19 cases in pregnant women and the general population. The frequency of cesarean deliveries is high, against guidelines recommendations.

CONCLUSION

Limited data on COVID-19 during preganacy, associated with a wide variation in the methodology make accurate data interpretation difficult.

摘要

目的

补充关于孕期感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的越来越多的证据,以便更好地为临床决策提供信息并优化患者预后。

方法

于2020年3月25日对相关数据库进行了系统检索,并于2020年4月10日进行了重复检索。对孕期任何时间感染SARS-CoV-2的孕妇报告进行了回顾和总结。

结果

我们总结了155名孕妇和118名新生儿的结局。证据表明,孕妇中重症冠状病毒病2019(COVID-19)病例的发生率与普通人群相似。剖宫产率很高,与指南建议相悖。

结论

孕期COVID-19的数据有限,且方法差异很大,难以进行准确的数据解读。

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