Sala T
ENT Department, Hospital of Mestre, Venice, Italy.
Arch Otorhinolaryngol. 1988;245(5):293-6. doi: 10.1007/BF00464634.
Transtympanic administration of gentamicin was used to treat patients with unilateral Menière's disease and was stopped at the first signs of damage to cochlear and/or vestibular function. Twenty-eight patients were treated between 1974 and 1981 and 34 patients were managed between 1981 and 1987. In the two groups of patients, objective vertigo disappeared in 85%, hearing improved in 26%, aural fullness disappeared in 78%, while tinnitus ceased altogether in 51% and became less intense in 24%. Our findings show that this kind of treatment can be used after unsuccessful medical therapy and prior to any labyrinthine or endolymphatic sac surgery.
采用庆大霉素经鼓膜给药治疗单侧梅尼埃病患者，一旦出现耳蜗和/或前庭功能损害的最初迹象即停止治疗。1974年至1981年间治疗了28例患者，1981年至1987年间治疗了34例患者。在这两组患者中，85%的患者客观眩晕消失，26%的患者听力改善，78%的患者耳胀满感消失，而耳鸣完全停止的患者占51%，耳鸣减轻的患者占24%。我们的研究结果表明，这种治疗方法可在药物治疗失败后、任何迷路或内淋巴囊手术之前使用。
