Dolev E, Tamir A, Leventon G
Med Hypotheses. 1983 Apr;10(4):353-8. doi: 10.1016/0306-9877(83)90002-6.
Aminoglycoside antibiotic drugs may cause ototoxicity and nephrotoxicity. Our hypothesis postulates that aminoglycosides cause ototoxicity by a mechanism of magnesium depletion in the hair cells of the cochlea. The same mechanism maybe responsible for nephrotoxicity caused by aminoglycosides.