Millward M J, Ganju V, Buck M
Department of Medical Oncology, Sir Charles Gairdner Hospital, Nedlands, WA.
Aust N Z J Med. 1988 Aug;18(5):693-5. doi: 10.1111/j.1445-5994.1988.tb00153.x.
We report a case of cardiac arrest occurring during an infusion of 5-fluorouracil where electrocardiograms suggested coronary artery spasm as the underlying event. Treatment with vasodilators and diltiazem, proved effective. This clinical presentation of 5-fluorouracil cardiotoxicity has not previously been described.
我们报告了一例在输注5-氟尿嘧啶期间发生心脏骤停的病例,心电图提示冠状动脉痉挛是潜在病因。使用血管扩张剂和地尔硫䓬治疗被证明有效。5-氟尿嘧啶心脏毒性的这种临床表现此前尚未见报道。