Breningstall G N, Lockman L A
Department of Pediatric Subspecialties, Park Nicollet Medical Center, Minneapolis, MN 55404.
Pediatr Neurol. 1988 Nov-Dec;4(6):366-70. doi: 10.1016/0887-8994(88)90085-9.
Two patients are reported with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes in whom CT documented massive focal brain swelling with midline shift concurrent with exacerbations of their conditions. Brain swelling producing mass effect should be recognized as a feature of MELAS.