Toho University, School of Psychosomatic medicine, 6-11-1 Omorinishi Ota-ku, Tokyo, Japan.
Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo, Japan.
BMC Pregnancy Childbirth. 2020 May 27;20(1):323. doi: 10.1186/s12884-020-03006-7.
Studies have shown that women of reproductive age develop eating disorders (EDs). Few studies have examined EDs in women by performing long-term follow-ups during pregnancy and after delivery. Our study aimed to identify relapse of EDs during pregnancy and after delivery as well as postpartum depression in women who had complete remission of EDs.
Of the 1008 patients with EDs who visited our outpatient clinic between 1994 and 2004, 55 experienced ED remission and pregnancy. Of these, 25 (21 with BN and 4 with AN) consented to participate in this study. Finally, 24 patients were included in this study after 1 patient was excluded owing to a miscarriage. They were interviewed every 2 weeks both during pregnancy and after giving birth. We used the Eating Attitudes Test-26 (EAT-26) and Edinburgh Postnatal Depression Scale (EPDS) as reference scales for diagnosing the EDs and the postpartum depression, respectively. We used a two-sided unpaired test for the statistical analysis.
Sixteen participants (67%) experienced ED relapse during pregnancy and twelve (50%) relapsed after birth. Twelve (50%) had postpartum depression, four of whom (33%) had low-birth-weight infants. Among the participants who did not have postpartum depression, there were no low-body-weight infants. There was no significant difference (p = 0.065) in birth weight between the postpartum depression and non-depression groups.
Our study revealed that recurrence of EDs and the occurrence of postpartum depression were higher in this population, indicating the need to closely monitor EDs both during pregnancy and after birth.
研究表明,育龄妇女会患上饮食失调症(EDs)。很少有研究通过在怀孕期间和分娩后进行长期随访来检查女性的 ED 情况。我们的研究旨在确定完全缓解 ED 的女性在怀孕期间和分娩后 ED 复发以及产后抑郁症的情况。
在 1994 年至 2004 年间,我们的门诊共接待了 1008 名 ED 患者,其中 55 名患者的 ED 得到缓解并怀孕。其中,25 名(21 名患有 BN,4 名患有 AN)同意参加本研究。最终,由于 1 名患者流产,排除 1 名患者后,共有 24 名患者纳入本研究。在怀孕期间和分娩后,他们每两周接受一次访谈。我们使用 Eating Attitudes Test-26(EAT-26)和 Edinburgh Postnatal Depression Scale(EPDS)分别作为诊断 ED 和产后抑郁症的参考量表。我们使用双侧非配对检验进行统计分析。
16 名参与者(67%)在怀孕期间出现 ED 复发,12 名(50%)在分娩后复发。12 名(50%)患有产后抑郁症,其中 4 名(33%)婴儿体重较低。在没有产后抑郁症的参与者中,没有低体重婴儿。产后抑郁症组和非抑郁症组之间的出生体重没有显著差异(p=0.065)。
我们的研究表明,该人群中 ED 复发和产后抑郁症的发生率较高,这表明需要在怀孕期间和分娩后密切监测 ED。