系统性红斑狼疮和狼疮性肾炎患者的尿滴虫病：病例报告。
Urinary balantidiasis in a patient with systemic lupus erythematosus and lupus nephritis: a case report.
机构信息
Division of Parasitology, Department of Preclinical Sciences, Faculty of Medicine, Thammasat University, Pathumthani, 12120, Thailand.
Department of Medical Technology Laboratory, Thammasat University Hospital, Pathumthani, Thailand.
出版信息
J Med Case Rep. 2020 May 28;14(1):63. doi: 10.1186/s13256-020-02389-7.
BACKGROUND
Balantidium coli, a parasitic unicellular ciliate, often causes asymptomatic balantidiasis of the colon, but extraintestinal disease may occur rarely in immunosuppressed individuals. Renal balantidiasis associated with systemic lupus erythematosus has not been reported before.
CASE PRESENTATION
We present a case of a 48-year-old Thai woman who presented with nephrotic syndrome due to systemic lupus erythematosus-related nephritis. Initially, few B. coli cysts were found in urine sediment, but these increased substantially following treatment with prednisolone. She made an uneventful recovery with 10 days of oral tetracycline therapy. No B. coli cysts were found in her stool.
CONCLUSION
The route of infection in our patient was unclear but is likely to have been orofecal. Neither her infection nor its treatment caused a deterioration in her renal function.
背景
结肠内寄生的纤毛原虫蓝氏贾第鞭毛虫常引起无症状的结肠贾第虫病，但在免疫抑制个体中，很少发生肠道外疾病。以前没有报道过与系统性红斑狼疮相关的肾脏贾第虫病。
病例介绍
我们报告了一例 48 岁的泰国女性，因系统性红斑狼疮相关肾炎导致肾病综合征。最初，尿液沉淀物中发现少量蓝氏贾第鞭毛虫包囊，但在泼尼松龙治疗后明显增加。她接受了 10 天的口服四环素治疗，病情平稳恢复。她的粪便中未发现蓝氏贾第鞭毛虫包囊。
结论
我们患者的感染途径尚不清楚，但可能是经口感染。她的感染及其治疗均未导致肾功能恶化。
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