Rüegsegger P, Steiger P, Felder M
Institute for Biomedical Engineering, University of Zurich, Switzerland.
Clin Rheumatol. 1988 Dec;7(4):486-91.
A good noninvasive means to quantitate the extent and course of bone loss in rheumatoid arthritis (RA) is currently not available. We report on ways of assessing arthritic bone changes by means of quantitative computed tomography (QCT). The visualization of lesions and the quantitation of bone density diminutions are based on a stack of forty thin computed tomograms and 3D reconstructions. A pilot study shows that QCT may be a useful tool in the noninvasive assessment of the progression of RA and that it may help to evaluate the efficacy of therapeutic procedures.
目前尚无一种很好的非侵入性方法来定量评估类风湿关节炎（RA）中骨质流失的程度和进程。我们报告了通过定量计算机断层扫描（QCT）评估关节炎性骨改变的方法。病变的可视化和骨密度降低的定量基于四十层薄计算机断层扫描图像堆栈和三维重建。一项初步研究表明，QCT可能是一种用于非侵入性评估RA病情进展的有用工具，并且可能有助于评估治疗程序的疗效。
