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Atypical Obstructive Pseudotumors in AIDS as the Initial Manifestation of Gastrointestinal Histoplasmosis.

作者信息

Hallo Alejandro, Camacho Malena, Rojas Alejandra, Mayancela Andres, Castillo Alberto

机构信息

Internal Medicine, Hospital de Especialidad Eugenio Espejo, Quito, ECU.

Internal Medicine, Hospital de Especialidades Eugenio Espejo, Quito, ECU.

出版信息

Cureus. 2020 Apr 22;12(4):e7775. doi: 10.7759/cureus.7775.

DOI:10.7759/cureus.7775
PMID:32461850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7243627/
Abstract

Histoplasma capsulatum is a dysmorphic fungus distributed worldwide commonly associated with pulmonary histoplasmosis. We report the case of an unusual presentation of gastrointestinal histoplasmosis leading to the obstruction of the intestinal lumen in a 30-year-old female, HIV positive, admitted to the hospital due to chronic abdominal pain and constipation. An initial abdominal CT revealed a mass in the sigmoid colon. A further colonoscopy showed an infiltrating, friable mass obstructing 80% of the lumen staining positive for H. capsulatum. The unspecific nature of the patient's symptoms along with the unusual presentation of the infection raises awareness about the importance of including new pathologies to differential diagnoses when treating AIDS patients.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c1/7243627/b9b995cbcfc8/cureus-0012-00000007775-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c1/7243627/0f62dff98722/cureus-0012-00000007775-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c1/7243627/b9b995cbcfc8/cureus-0012-00000007775-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c1/7243627/0f62dff98722/cureus-0012-00000007775-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8c1/7243627/b9b995cbcfc8/cureus-0012-00000007775-i02.jpg

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本文引用的文献

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Diagnosis of Progressive Disseminated Histoplasmosis in Advanced HIV: A Meta-Analysis of Assay Analytical Performance.晚期人类免疫缺陷病毒（HIV）感染者中进行性播散型组织胞浆菌病的诊断：检测分析性能的荟萃分析
J Fungi (Basel). 2019 Aug 18;5(3):76. doi: 10.3390/jof5030076.
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Diagnostic accuracy cohort study and clinical value of the Histoplasma urine antigen (ALPHA Histoplasma EIA) for disseminated histoplasmosis among HIV infected patients: A multicenter study.播散性组织胞浆菌病患者中 HIV 感染者尿抗原 Histoplasma（ALPHA Histoplasma EIA）的诊断准确性队列研究及临床价值：一项多中心研究。
PLoS Negl Trop Dis. 2018 Nov 5;12(11):e0006872. doi: 10.1371/journal.pntd.0006872. eCollection 2018 Nov.
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Histoplasma capsulatum antigen detection tests as an essential diagnostic tool for patients with advanced HIV disease in low and middle income countries: A systematic review of diagnostic accuracy studies.
荚膜组织胞浆菌抗原检测试验作为中低收入国家晚期 HIV 疾病患者的重要诊断工具：诊断准确性研究的系统评价。
PLoS Negl Trop Dis. 2018 Oct 19;12(10):e0006802. doi: 10.1371/journal.pntd.0006802. eCollection 2018 Oct.
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A Case of Isolated Gastrointestinal Histoplasmosis.一例孤立性胃肠道组织胞浆菌病
Cureus. 2018 Jul 9;10(7):e2951. doi: 10.7759/cureus.2951.
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Antigen negative gastrointestinal histoplasmosis in an AIDS patient.一名艾滋病患者的抗原阴性胃肠道组织胞浆菌病。
Am J Case Rep. 2014 Feb 26;15:90-3. doi: 10.12659/AJCR.889940. eCollection 2014.
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