Andrawes Peter, Hill David A, Ng Marilyn, Raval Ami, Culliford Alfred
Plastic, Reconstructive and Hand Surgery, Northwell Health/Donald and Barbara Zucker School of Medicine, Staten Island University Hospital, Staten Island, USA.
Plastic Surgery, Houston Methodist Hospital, Houston, USA.
Cureus. 2020 Apr 23;12(4):e7801. doi: 10.7759/cureus.7801.
Malignant fibrous histiocytoma (MFH) is an undifferentiated high-grade pleomorphic sarcoma and is considered the most common primary soft tissue sarcoma in adults. MFH is known to arise in the trunk, extremities and retroperitoneum although it can arise anywhere in the body.MFH of the skin is uncommon and even less frequent is the involvement of the scalp, especially with skull invasion. Most of the MFH cases present as a gradually growing lesion over a period of one to two years and is associated with ulceration and hemorrhage in most of the cases. Treatment of MFH is usually surgical resection. We present a case of MFH in an 85-year-old gentleman that was invading the skull which required a multidisciplinary surgical treatment for resection and microvascular free flap reconstruction.
恶性纤维组织细胞瘤（MFH）是一种未分化的高级别多形性肉瘤，被认为是成人中最常见的原发性软组织肉瘤。已知MFH可发生于躯干、四肢和腹膜后，尽管它可在身体的任何部位发生。皮肤MFH并不常见，而头皮受累甚至更为罕见，尤其是伴有颅骨侵犯时。大多数MFH病例表现为在1至2年的时间内逐渐生长的病变，并且在大多数病例中与溃疡和出血有关。MFH的治疗通常是手术切除。我们报告一例85岁男性的MFH病例，该病例侵犯颅骨，需要多学科手术治疗以进行切除和微血管游离皮瓣重建。
