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肺癌碳离子放疗后局部复发的挽救性手术:一例报告

Salvage surgery for local recurrence after carbon ion radiotherapy for lung cancer: A case report.

作者信息

Hara Kantaro, Izumi Nobuhiro, Tsukioka Takuma, Komatsu Hiroaki, Inoue Hidetoshi, Miyamoto Hikaru, Nishiyama Noritoshi

机构信息

Department of Thoracic Surgery, Osaka City University Hospital, Japan.

出版信息

Respir Med Case Rep. 2020 May 16;30:101091. doi: 10.1016/j.rmcr.2020.101091. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101091
PMID:32461884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7240179/
Abstract

BACKGROUND

The good local control rate of radiation therapy has been reported due to recent advances in irradiation technology. Carbon ion radiation therapy (CIRT) has been shown to be effective for early lung cancer. We report a case of performing salvage surgery on the local recurrence of lung cancer after CIRT.

CASE PRESENTATION

A 79-year-old man was referred to our hospital for treatment of local recurrence of left lung cancer at fifty nine months after CIRT. We performed wedge resection for diagnostic purposes. It was diagnosed as squamous cell carcinoma and was regarded as local recurrence. Subsequently, we performed left upper lobectomy and mediastinal lymph node dissection. The patient had recurrent lesions at 4 months after surgery and died 10 months after surgery.

CONCLUSIONS

Surgery was safe even after CIRT. We considered that salvage surgery after CIRT may be one of the options of local control therapy for lung cancer.

摘要

背景

由于放射治疗技术的最新进展,已有报道称放射治疗具有良好的局部控制率。碳离子放射治疗(CIRT)已被证明对早期肺癌有效。我们报告一例CIRT后肺癌局部复发行挽救性手术的病例。

病例介绍

一名79岁男性在CIRT后59个月因左肺癌局部复发被转诊至我院。为明确诊断,我们进行了楔形切除术。诊断为鳞状细胞癌,考虑为局部复发。随后,我们进行了左上叶切除术和纵隔淋巴结清扫术。患者术后4个月出现复发病灶,术后10个月死亡。

结论

即使在CIRT后手术也是安全的。我们认为CIRT后的挽救性手术可能是肺癌局部控制治疗的选择之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/454a/7240179/b16b06854868/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/454a/7240179/56163d488cfd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/454a/7240179/b16b06854868/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/454a/7240179/56163d488cfd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/454a/7240179/b16b06854868/gr2.jpg

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本文引用的文献

1
Salvage surgery for local recurrence after carbon ion radiotherapy for patients with lung cancer.肺癌患者碳离子放疗后局部复发的挽救性手术
Eur J Cardiothorac Surg. 2016 May;49(5):1503-9. doi: 10.1093/ejcts/ezv348. Epub 2015 Oct 14.
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Thoracoscopic lobectomy as salvage surgery for local recurrence of non-small cell lung cancer after carbon ion radiotherapy in an initially operable patient.对于一名初始可手术的患者,在碳离子放疗后非小细胞肺癌局部复发时,采用胸腔镜肺叶切除术作为挽救性手术。
Ann Thorac Cardiovasc Surg. 2014;20 Suppl:501-4. doi: 10.5761/atcs.cr.13-00223. Epub 2014 Feb 4.
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