Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, India.
Chem Commun (Camb). 2020 Jul 28;56(60):8376-8379. doi: 10.1039/d0cc01460e.
Herein, β-branched carbonyl compounds were synthesised via the α-alkylation of ketones with secondary alcohols under "borrowing hydrogen" catalysis. A wide range of secondary alcohols, including various cyclic, acyclic, symmetrical, and unsymmetrical alcohols, have been successfully applied under the developed reaction conditions. A manganese(i) complex bearing a phosphine-free multifunctional ligand catalysed the reaction and produced water as the sole byproduct.
本文通过酮与仲醇在“氢 borrowing”催化下的α-烷基化反应合成了β-支链羰基化合物。在开发的反应条件下，成功应用了多种仲醇，包括各种环状、无环、对称和不对称的醇。一种含有无膦多功能配体的锰(i)配合物催化了该反应，仅生成水作为唯一的副产物。
