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[自发性高血压大鼠的行为和代谢特征]

[Behavioral and metabolic features of spontaneously hypertensive rats].

作者信息

Bachmanov A A, Dmitriev Iu S, Maslennikova L S

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1988 Nov;74(11):1677-83.

PMID:3246284
Abstract

12-week old spontaneously hypertensive (SHR) rats in comparison with normotensive Wistar-Kyoto (WKY) rats had an enhanced behavioural activity associated with exploratory motivation and a lower one associated with the fear motivation, their daily activity and the activity associated with alternating illumination were also higher whereas their defecation was lower. No difference in oxygen metabolism was found at 12 weeks of age. 20-week SHR rats had a higher common oxygen consumption and lower pO2 and blood circulation velocity in the sensomotor area of the brain cortex.

摘要

与正常血压的Wistar-Kyoto(WKY)大鼠相比,12周龄的自发性高血压(SHR)大鼠具有与探索动机相关的增强的行为活动和与恐惧动机相关的较低行为活动,它们的日常活动以及与交替光照相关的活动也更高,而它们的排便则较少。在12周龄时未发现氧代谢有差异。20周龄的SHR大鼠在大脑皮层感觉运动区的共同耗氧量较高,pO2和血液循环速度较低。

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