Charles River, 6-9 Spire Green Centre, Harlow, Essex CM19 5TR, United Kingdom.
J Chem Inf Model. 2020 Sep 28;60(9):4120-4123. doi: 10.1021/acs.jcim.0c00101. Epub 2020 May 28.
This viewpoint is intended to counterbalance some recent publications describing large-scale virtual screening by illustrating how success in launching drug discovery projects has been achieved with much more modest resources. Two examples of small-scale virtual screening that led to the discovery of clinical candidates are cited in favor of this argument.
这种观点旨在平衡一些最近描述大规模虚拟筛选的出版物，通过举例说明如何用更适度的资源成功启动药物发现项目。为了支持这一观点，引用了两个小规模虚拟筛选的例子，这些例子导致了临床候选药物的发现。
