糖多孢红霉菌烈性噬菌体SE-3的特性分析
Characterization of SE-3, a virulent bacteriophage of Saccharopolyspora erythraea.
作者信息
Smorawinska M, Denis F, Déry C V, Magny P, Brzezinski R
机构信息
Département de Microbiologie, Faculté de Médecine, Université de Sherbrooke, Québec, Canada.
出版信息
J Gen Microbiol. 1988 Jul;134(7):1773-8. doi: 10.1099/00221287-134-7-1773.
SE-3 is a virulent bacteriophage isolated from a large-scale culture of Saccharopolyspora erythraea, an erythromycin producer. The host range of the phage is narrow, limited to some strains of this species. Another strain of Sac. erythraea, and a strain of Sac. hirsuta, are able to adsorb phage particles but do not sustain their complete multiplication. SE-3 is closely related to the phage SE-5 as shown by DNA restriction mapping. The differences between SE-3 and SE-5 genomes are apparently limited to two DNA segments flanked by short inverted repeats, visualized by electron microscopy.
SE-3是一种从红霉素产生菌糖多孢红霉菌的大规模培养物中分离得到的烈性噬菌体。该噬菌体的宿主范围狭窄，仅限于该物种的某些菌株。另一株糖多孢红霉菌和一株赫氏糖多孢菌能够吸附噬菌体颗粒，但不能支持其完全增殖。如DNA限制性图谱所示，SE-3与噬菌体SE-5密切相关。通过电子显微镜观察，SE-3和SE-5基因组之间的差异显然仅限于两个由短反向重复序列侧翼的DNA片段。
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