Section of Cardiology, Baylor School of Medicine and the Michael E. DeBakey VA Medical Center, Houston, Texas; Department of Cardiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Heart, New York, New York.
Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
Am J Cardiol. 2020 Jul 15;127:149-155. doi: 10.1016/j.amjcard.2020.04.012. Epub 2020 Apr 26.
The 2016 American Heart Association Scientific Statement on sleep duration and cardiovascular risk suggested that optimal sleep duration is critical for cardiovascular health, with both long and short sleep duration associated with adverse health outcomes. We examined the relation between sleep duration and cardiovascular health among the general population in the United States from 2005 to 2016. We sought to investigate associations between sleep duration and the prevalence of coronary artery disease, heart failure (HF), stroke, hypertension, diabetes mellitus (DM), and hyperlipidemia. Using the National Health and Nutrition Examination Survey, we identified all patients with HF, coronary artery disease, hypertension, hyperlipidemia, DM, and stroke from 2005 to 2016. Multivariable logistic regression analyses were performed to adjust for age, sex, body mass index (BMI), marital status, educational level, physical activity, sedentary activity, depression, blood pressure, lipid profiles, and hemoglobin. In total, 32,152 National Health and Nutrition Examination Survey participants responded to the sleep survey. Both short sleepers (<7 hours, n = 12,027) and long sleepers (>9 hours, n = 1,058) were older and more likely to have a higher BMI than optimal sleepers (7 to 9 hours, n = 19,067; all p values <0.05). After adjusting for confounding variables and in comparison to those with optimal sleep duration, short sleep duration was associated with a higher prevalence of previous stroke (odds ratio [OR] 1.45; 95% confidence intervals [CI] 1.23 to 1.70), HF (OR 1.65; 95% CI 1.40 to 1.95), DM (OR 1.35; 95% CI 1.23 to 1.49), and hyperlipidemia (OR 1.12; 95% CI 1.04 to 1.22), whereas long sleep duration was associated with a higher prevalence of previous stroke (OR 1.81; 95% CI 1.37 to 2.34) and HF (OR 1.47; 95% CI 1.08 to 1.97). In conclusion, both long and short sleep durations were associated with poor cardiovascular health in this cross-sectional study.
2016 年美国心脏协会科学声明指出，睡眠时长与心血管风险有关，过长或过短的睡眠时长均与不良健康结果相关。我们在美国 2005 年至 2016 年的普通人群中研究了睡眠时长与心血管健康之间的关系。我们试图调查睡眠时长与冠心病、心力衰竭（HF）、中风、高血压、糖尿病（DM）和高脂血症患病率之间的关系。我们使用国家健康和营养检查调查（National Health and Nutrition Examination Survey），从 2005 年至 2016 年确定了所有 HF、冠心病、高血压、高脂血症、DM 和中风患者。多变量逻辑回归分析用于调整年龄、性别、体重指数（BMI）、婚姻状况、教育水平、体力活动、久坐活动、抑郁、血压、血脂谱和血红蛋白。共有 32152 名国家健康和营养检查调查参与者对睡眠调查做出了回应。短睡眠者（<7 小时，n=12027）和长睡眠者（>9 小时，n=1058）均比理想睡眠者（7 至 9 小时，n=19067）年龄更大，BMI 更高（所有 p 值<0.05）。在调整混杂变量后，与具有理想睡眠时长的人相比，短睡眠时长与更高的既往中风（比值比[OR]1.45；95%置信区间[CI]1.23 至 1.70）、HF（OR 1.65；95% CI 1.40 至 1.95）、DM（OR 1.35；95% CI 1.23 至 1.49）和高脂血症（OR 1.12；95% CI 1.04 至 1.22）患病率相关，而长睡眠时长与更高的既往中风（OR 1.81；95% CI 1.37 至 2.34）和 HF（OR 1.47；95% CI 1.08 至 1.97）患病率相关。总之，在这项横断面研究中，长睡眠和短睡眠都与心血管健康不良有关。
