葛根对血管疾病的影响。
Effects of Root on Vascular Diseases.
机构信息
"VINČA" Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, University of Belgrade, Department of Physical Chemistry, Belgrade, Serbia.
Serbian Academy of Sciences and Arts, Belgrade, Serbia.
出版信息
Curr Vasc Pharmacol. 2021;19(4):359-369. doi: 10.2174/1570161118666200529111314.
BACKGROUND
Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and bitterwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich natural source of iridoids, secoiridoids, xantones, flavonoids, triterpenoids, and carbohydrates. Medicinal plants from Gentiana species have anti-oxidant, anti-inflammatory, anti-mitogenic, anti-proliferative, and lipidlowering effects, as well as a cardioprotective, hypotensive, vasodilator and anti-platelet activities.
OBJECTIVE
We reviewed the recent literature related to the effects of Gentiana species, and their active components on vascular diseases.
METHODS
Data used for this review were obtained by searching the electronic database [PUBMED/ MEDLINE 1973 - February 2020]. The primary data search terms of interest were: Gentiana lutea, Gentienacea family, phytochemistry, vascular diseases, treatment of vascular diseases, antioxidant, anti-inflammatory, anti-atherogenic.
CONCLUSION
Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially useful drugs for the management of vascular diseases.
背景
秦艽（GL），俗称黄花秦艽、苦根和苦草，属于龙胆科。GL 属于龙胆属，是裂环烯醚萜类、环烯醚萜类、口山酮类、黄酮类、三萜类和碳水化合物的丰富天然来源。龙胆属植物具有抗氧化、抗炎、抗有丝分裂、抗增殖和降血脂作用，以及心脏保护、降压、血管扩张和抗血小板作用。
目的
我们综述了与龙胆属植物及其活性成分对血管疾病影响相关的近期文献。
方法
本综述使用的资料来源于电子数据库[PUBMED/MEDLINE 1973 年-2020 年 2 月]。主要数据检索词为：秦艽、龙胆科、植物化学、血管疾病、血管疾病治疗、抗氧化、抗炎、抗动脉粥样硬化。
结论
龙胆属植物及其成分影响与血管疾病发展和进展相关的许多不同因素。因此，基于龙胆属的治疗方法可能是治疗血管疾病的有用药物。
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