Jeyachandran Praveen, Bontha Srikanth, Bodhak Subhadip, Balla Vamsi Krishna, Kundu Biswanath, Doddamani Mrityunjay
Additive Manufacturing Laboratory, Department of Mechanical Engineering, National Institute of Technology Karnataka, Surathkal, 575025, India; Advanced Manufacturing Laboratory, Department of Mechanical Engineering, National Institute of Technology Karnataka, Surathkal, 575025, India.
Additive Manufacturing Laboratory, Department of Mechanical Engineering, National Institute of Technology Karnataka, Surathkal, 575025, India.
J Mech Behav Biomed Mater. 2020 Aug;108:103830. doi: 10.1016/j.jmbbm.2020.103830. Epub 2020 Apr 30.
Bioactive glass (BAG) is a well-known biomaterial that can form a strong bond with hard and soft tissues and can also aid in bone regeneration. In this study, BAG is added to a polymer to induce bioactivity and to realize fused filament fabrication (FFF) based printing of polymer composites for potential orthopaedic implant applications. BAG (5, 10, and 20 wt%) is melt compounded with high density polyethylene (HDPE) and subsequently extruded into feedstock filament for FFF-printing. Tensile tests on developed filaments reveal that they are stiff enough to resist forces exerted during the printing process. Micrography of printed HDPE/BAG reveals perfect diffusion of raster interface indicating proper selection of printing parameters. Micrography of freeze fractured prints shows the homogeneous distribution and good dispersion of filler across the matrix. The tensile, flexural, and compressive modulus of FFF-printed HDPE/BAG parts increases with filler addition. BAG addition to the HDPE matrix enhances flexural and compressive strength. The tensile and flexural behaviour of FFF-prints is comparable to injection molded counterparts. Property maps exhibit the merits of present study over the existing literature pertaining to desired bone properties and polymer composites used in biomedical applications. It is envisioned that the development of HDPE/BAG composites for FFF-printing can lead to possible orthopaedic implants and scaffolds to mimic the bone properties in customised anatomical sites or injuries.
生物活性玻璃（BAG）是一种知名的生物材料，它能与硬组织和软组织形成牢固的结合，还能促进骨再生。在本研究中，将BAG添加到聚合物中以诱导生物活性，并实现基于熔融沉积成型（FFF）的聚合物复合材料打印，用于潜在的骨科植入应用。将BAG（5%、10%和20%重量）与高密度聚乙烯（HDPE）进行熔融共混，随后挤出成用于FFF打印的原料丝材。对所制备丝材的拉伸试验表明，它们具有足够的刚度来抵抗打印过程中施加的力。打印的HDPE/BAG的显微照片显示光栅界面完美扩散，表明打印参数选择得当。冷冻断裂打印件的显微照片显示填料在整个基体中均匀分布且分散良好。FFF打印的HDPE/BAG部件的拉伸、弯曲和压缩模量随填料添加量的增加而提高。向HDPE基体中添加BAG可提高弯曲强度和压缩强度。FFF打印件的拉伸和弯曲性能与注塑成型件相当。性能图谱展示了本研究相对于现有文献在生物医学应用中所需骨性能和聚合物复合材料方面的优势。可以设想，用于FFF打印的HDPE/BAG复合材料的开发可能会带来定制解剖部位或损伤处模仿骨性能的骨科植入物和支架。
