Kouiss Youssef, Aynaou Mohammed, Houmaidi Amine El, Mhanna Tarik, Ahmed Yacoub, Ouraghi Abdelghani, Miri Achraf, Bennani Amal, Barki Ali
Department of Urology, Mohamed VI University Hospital, Oujda, Morocco.
Department of Urology, Mohamed VI University Hospital, Oujda, Morocco.
Int J Surg Case Rep. 2020;71:187-191. doi: 10.1016/j.ijscr.2020.04.091. Epub 2020 May 11.
Penile calciphylaxis is a rare disease whose diagnosis is not easy. It is associated with chronic renal failure. It is a result of media calcification and blood vessels' fibrosis such as penile arteries that eventually lead to gangrene formation in extremities and penis. Calcific uremic arteriolopathy is commonly associated with secondary hyperparathyroidism and high level of calcium and phosphate.
In this paper, we report a case of penile necrosis induced by calciphylaxis associated with chronic renal failure and diabetic macroangiopathy. We performed a partial and total amputation in two stages because of the wound infection. The patient died one week after a total penectomy.
The skin biopsy is the gold standard for the diagnosis despite being a risky process. In most cases, appropriate medical management is advocated. The treatment of this pathology is still controversial.
The management of this rare situation is controversial, and its diagnosis is still difficult due to the scarcity of reported cases.
阴茎血管钙化防御是一种罕见疾病，诊断不易。它与慢性肾衰竭相关。它是中膜钙化及诸如阴茎动脉等血管纤维化的结果，最终导致肢体和阴茎坏疽形成。钙化性尿毒症小动脉病通常与继发性甲状旁腺功能亢进以及高钙和高磷水平相关。
在本文中，我们报告一例因血管钙化防御导致阴茎坏死的病例，该病例与慢性肾衰竭和糖尿病大血管病变相关。由于伤口感染，我们分两个阶段进行了部分和全部截肢。患者在阴茎全切术后一周死亡。
尽管皮肤活检是一个有风险的过程，但仍是诊断的金标准。在大多数情况下，提倡进行适当的药物治疗。这种病理状况的治疗仍存在争议。
这种罕见情况的处理存在争议，且由于报道病例稀少，其诊断仍然困难。
