Campbell Rebecca A, Alzweri Laith M, Sopko Nikolai A, Macura Katarzyna J, Burnett Arthur L
Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, OH 44106, USA.
The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Urol Case Rep. 2017 May 11;13:113-116. doi: 10.1016/j.eucr.2017.03.008. eCollection 2017 Jul.
Penile calciphylaxis is a rare phenomenon of penile necrosis observed in patients with hemodialysis-dependent end-stage renal failure. Multiple treatments have been proposed including conservative management, surgical debridement and penectomy; yet, the prognosis remains extremely poor. Here, we describe a patient with protracted resolution of dry gangrene of the glans, which failed conservative management of wound care and pain management. Radiological studies revealed extensive calcification of abdominal aorta and branching vessels including the penile arteries. Due to intolerable pain, the patient required total penectomy. Earlier surgical intervention guided by findings on radiological studies may improve quality of life in this population.
阴茎钙化防御是在依赖血液透析的终末期肾衰竭患者中观察到的一种罕见的阴茎坏死现象。已经提出了多种治疗方法，包括保守治疗、手术清创和阴茎切除术；然而，预后仍然极差。在此，我们描述了一名龟头干性坏疽长期消退的患者，其伤口护理和疼痛管理的保守治疗失败。影像学研究显示腹主动脉和包括阴茎动脉在内的分支血管广泛钙化。由于无法忍受的疼痛，患者需要进行全阴茎切除术。根据影像学研究结果进行早期手术干预可能会改善这一人群的生活质量。
