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心脏和肾脏移植受者的生活质量水平:一项多中心研究。

Level of Life Quality in Heart and Kidney Transplant Recipients: A Multicenter Study.

作者信息

Milaniak Irena, Rużyczka Ewa Wilczek, Dębska Grażyna, Król Bogumiła, Wierzbicki Karol, Tomaszek Lucyna, Przybyłowski Piotr

机构信息

Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland; Department of Cardiovascular and Transplantology, John Paul II Hospital, Krakow, Poland.

Faculty of Psychology, Andrzej Frycz Modrzewski Krakow University, Krakow, Poland.

出版信息

Transplant Proc. 2020 Sep;52(7):2081-2086. doi: 10.1016/j.transproceed.2020.03.038. Epub 2020 May 26.

DOI:10.1016/j.transproceed.2020.03.038
PMID:32471630
Abstract

OBJECTIVE

The main objective of the researchers was to determine the level of life quality among heart and kidney transplant recipients depending on the time and type of the transplant.

METHODS

The study was conducted using standardized questionnaires: the 36-Item Short-Form Health Survey, Life Orientation Test-Revised, and Hospital Anxiety and Depression Scale. The study included 146 recipients (109 heart transplant recipients and 37 kidney transplant recipients) from 1 to 26 years after the transplantation surgery (mean 9 years).

RESULTS

The mean age of the study group was 52 years. The mean time since organ transplantation was 10 years for heart transplantation and 4.3 years for kidney transplantation. The study group obtained a slightly lower score for quality of life compared to the general population. In the Physical Component Summary (PCS), the study participants obtained the highest mean for the domain bodily pain (47.6), while the lowest score was in the domain role physical (41.82). As for the Mental Component Summary (MCS), the highest mean was obtained for the domain vitality (50.57), whereas the lowest one was for the domain role emotional (43.38). In 33% of the participants, risk of depression was identified. Statistically significant differences were observed depending on the type of the transplanted organ in the PCS for the domains general health, physical functioning, and bodily pain and the MCS for role emotional and social functioning. The statistically significant predictors for the PCS domain were the type of transplanted organ, recipients' age, and occurrence of anxiety. In turn, the predictor for the MCS was the occurrence of depression.

CONCLUSIONS

The quality of life (QOL) assessment varies between kidney and heart transplant recipients. The QOL is determined by the recipients' age and the occurrence of anxiety and depression. The obtained QOL assessment results are slightly lower than those in the general population.

摘要

目的

研究人员的主要目的是根据移植时间和类型确定心脏和肾脏移植受者的生活质量水平。

方法

该研究使用标准化问卷进行:36项简短健康调查、生活取向测试修订版和医院焦虑抑郁量表。该研究纳入了146名移植手术后1至26年(平均9年)的受者(109名心脏移植受者和37名肾脏移植受者)。

结果

研究组的平均年龄为52岁。心脏移植术后器官移植的平均时间为10年,肾脏移植为4.3年。与普通人群相比,研究组的生活质量得分略低。在身体成分总结(PCS)中,研究参与者在身体疼痛领域的平均得分最高(47.6),而在身体角色领域的得分最低(41.82)。至于心理成分总结(MCS),活力领域的平均得分最高(50.57),而情感角色领域的得分最低(43.38)。在33%的参与者中,发现有抑郁风险。在PCS的一般健康、身体功能和身体疼痛领域以及MCS的情感角色和社会功能领域,根据移植器官的类型观察到统计学上的显著差异。PCS领域的统计学显著预测因素是移植器官的类型、受者年龄和焦虑的发生。反过来,MCS的预测因素是抑郁的发生。

结论

肾脏和心脏移植受者的生活质量(QOL)评估有所不同。QOL由受者年龄以及焦虑和抑郁的发生情况决定。获得的QOL评估结果略低于普通人群。

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