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Gene Editing to the Rescue: Reversal of Social Deficits Associated with MECP2 Duplication.

作者信息

Yu Zi-Xian, Wang Dan-Yang, Xu Xiao-Hong

机构信息

Institute of Neuroscience, State Key Laboratory of Neuroscience, Chinese Academy of Sciences Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.

University of the Chinese Academy of Sciences, Beijing, 100049, China.

出版信息

Neurosci Bull. 2020 Jun;36(6):567-569. doi: 10.1007/s12264-020-00522-6. Epub 2020 May 29.

DOI:10.1007/s12264-020-00522-6
PMID:32472288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7270302/
Abstract
摘要

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Cell. 2020 Apr 2;181(1):136-150. doi: 10.1016/j.cell.2020.03.023.
2
Reversal of Social Recognition Deficit in Adult Mice with MECP2 Duplication via Normalization of MeCP2 in the Medial Prefrontal Cortex.通过内侧前额叶皮质中 MeCP2 的正常化来逆转 MECP2 重复的成年小鼠的社交识别缺陷。
Neurosci Bull. 2020 Jun;36(6):570-584. doi: 10.1007/s12264-020-00467-w. Epub 2020 Mar 7.
3
Cardiopulmonary Comorbidity, Radiomics and Machine Learning, and Therapeutic Regimens for a Cerebral fMRI Predictor Study in Psychotic Disorders.用于精神病性障碍脑功能磁共振成像预测研究的心肺合并症、影像组学与机器学习及治疗方案
Neurosci Bull. 2019 Oct;35(5):955-957. doi: 10.1007/s12264-019-00409-1. Epub 2019 Jul 10.
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Dopamine D4 Receptor Gene Associated with the Frontal-Striatal-Cerebellar Loop in Children with ADHD: A Resting-State fMRI Study.多巴胺 D4 受体基因与 ADHD 儿童额-纹状体-小脑环路的关联：一项静息态 fMRI 研究。
Neurosci Bull. 2018 Jun;34(3):497-506. doi: 10.1007/s12264-018-0217-7. Epub 2018 Mar 21.
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Gamma Oscillation Dysfunction in mPFC Leads to Social Deficits in Neuroligin 3 R451C Knockin Mice.mPFC 中的伽马振荡功能障碍导致神经连接蛋白 3 R451C 敲入小鼠的社交缺陷。
Neuron. 2018 Mar 21;97(6):1253-1260.e7. doi: 10.1016/j.neuron.2018.02.001. Epub 2018 Mar 1.
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Neurobiol Dis. 2015 Apr;76:37-45. doi: 10.1016/j.nbd.2015.01.001. Epub 2015 Jan 30.