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ASO Author Reflections: Transitioning From Morphology to Transcriptomics in Capturing Tumor Biology.

作者信息

Takahashi Hideo, Oshi Masanori, Asaoka Mariko, Ishikawa Takashi, Endo Itaru, Takabe Kazuaki

机构信息

Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Department of Surgery, Yokohama City University, Yokohama, Japan.

出版信息

Ann Surg Oncol. 2020 Oct;27(11):4486-4487. doi: 10.1245/s10434-020-08680-7. Epub 2020 May 29.

DOI:10.1245/s10434-020-08680-7
PMID:32472409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7501179/
Abstract
摘要

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本文引用的文献

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Molecular Biological Features of Nottingham Histological Grade 3 Breast Cancers.诺丁汉组织学分级 3 级乳腺癌的分子生物学特征。
Ann Surg Oncol. 2020 Oct;27(11):4475-4485. doi: 10.1245/s10434-020-08608-1. Epub 2020 May 20.
2
A Novel 4-Gene Score to Predict Survival, Distant Metastasis and Response to Neoadjuvant Therapy in Breast Cancer.一种预测乳腺癌生存、远处转移及新辅助治疗反应的新型四基因评分
Cancers (Basel). 2020 May 2;12(5):1148. doi: 10.3390/cancers12051148.
3
Lymphovascular invasion in breast cancer is associated with gene expression signatures of cell proliferation but not lymphangiogenesis or immune response.乳腺癌中的淋巴管侵犯与细胞增殖的基因表达特征相关,但与淋巴管生成或免疫反应无关。
Breast Cancer Res Treat. 2020 Jun;181(2):309-322. doi: 10.1007/s10549-020-05630-5. Epub 2020 Apr 13.
4
Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate.高突变率乳腺癌中具有侵袭性生物学表型和抗肿瘤免疫的平衡。
Sci Rep. 2020 Feb 5;10(1):1852. doi: 10.1038/s41598-020-58995-4.
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High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer.在三阴性乳腺癌中,高 MYC mRNA 表达比 MYC DNA 扩增更具临床相关性。
Int J Mol Sci. 2019 Dec 28;21(1):217. doi: 10.3390/ijms21010217.
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Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients.肿瘤异质性与乳腺癌患者免疫反应减弱和预后不良相关。
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