Particle and Interfacial Technology Group (PaInT), Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent 9000, Belgium.
Research Unit of Food Microbiology and Food Preservation, part of Food2Know, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent 9000, Belgium.
Food Chem. 2020 Oct 15;327:126970. doi: 10.1016/j.foodchem.2020.126970. Epub 2020 May 5.
The self-assembly of Tween 80 (T80) micelles loaded with plant-based oregano essential oil (OR) and trans-cinnamaldehyde (TCA) was studied. The effect of different factors, including the surfactant to oil ratio, the presence of sodium chloride, thermal treatment, and dilution on their formation and physicochemical stability was evaluated. The creation of nano-cargos was confirmed by TEM. The self-associated structures had z-average droplet diameters of 92 to 337 nm without any energy input. Whereas addition of 10% (w/v) NaCl prevented the formation of oregano essential oil nano-assemblies of T80, swollen micelles containing TCA were successfully produced. Moreover, the OR or TCA loaded-micelles had only a slight droplet size variation upon thermal treatment. Ultimately, their antibacterial activity analysis against some food pathogens revealed that the encapsulation of OR and TCA within micelles crucially improved their antibacterial activity. These straightforward and cost-effective designed systems can be applicable in different products, including foods and agrochemicals.
研究了负载植物牛至精油（OR）和反式肉桂醛（TCA）的 Tween 80（T80）胶束的自组装。评估了不同因素，包括表面活性剂与油的比例、氯化钠的存在、热处理和稀释对其形成和物理化学稳定性的影响。通过 TEM 确认了纳米载体的形成。自组装结构在没有任何能量输入的情况下具有 92 至 337nm 的 z 均粒径。然而，添加 10%（w/v）NaCl 会阻止 T80 牛至精油纳米组装体的形成，但成功制备了含有 TCA 的溶胀胶束。此外，负载 OR 或 TCA 的胶束在热处理后仅略有粒径变化。最终，它们对一些食源性病原体的抗菌活性分析表明，OR 和 TCA 包封在胶束中可显著提高其抗菌活性。这些简单且具有成本效益的设计系统可适用于包括食品和农用化学品在内的不同产品。
