视神经脊髓炎谱系障碍还是胶质纤维酸性蛋白星形细胞病？一例报告。
NMOSD or GFAP astrocytopathy? A case report.
作者信息
Zhang Yue, Bhekharee Abhijeet Kumar, Zhang Xiang
机构信息
Department of Neurology, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Road, Shanghai 200040, China.
Shanghai Medical College, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
出版信息
Mult Scler Relat Disord. 2020 Aug;43:102202. doi: 10.1016/j.msard.2020.102202. Epub 2020 May 22.
We describe a 43-year-old female whose manifestations fulfilled the diagnostic criteria of aquaporin-4 IgG negative neuromyelitis optica spectrum disorders (NMOSD). High titer of glial fibrillary acidic protein (GFAP) antibody was detected in cerebrospinal fluid. In this case, some symptoms pertained to NMOSD and some to GFAP antibody-related disorders. The patient had a good response to corticosteroids.
我们描述了一位43岁的女性，其临床表现符合水通道蛋白4免疫球蛋白G阴性视神经脊髓炎谱系障碍（NMOSD）的诊断标准。脑脊液中检测到高滴度的胶质纤维酸性蛋白（GFAP）抗体。在该病例中，一些症状与NMOSD相关，一些与GFAP抗体相关疾病有关。该患者对皮质类固醇治疗反应良好。
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