Department of General Medicine, Government Medical College Hospital, Chandigarh, India.
Department of Pathology, Government Medical College Hospital, Chandigarh, India.
Int J Mycobacteriol. 2020 Apr-Jun;9(2):216-219. doi: 10.4103/ijmy.ijmy_4_20.
Disseminated tuberculosis (DTB) often presents with protean clinical manifestations that often leads to potential diagnostic dilemmas. The nonspecific features may include pyrexia of unknown origin, hepatosplenomegaly, lymphadenopathy, meningitis, and a variety of hematological abnormalities, namely anemia, pancytopenia, and leukemoid reaction. Tuberculosis is one of the nonhematopoietic diseases that has been reported in conjunction with myelofibrosis. We, hereby, report a case of DTB with massive splenomegaly, severe pancytopenia, and marrow fibrosis.
播散性结核（DTB）常表现出多样的临床表现，这往往导致潜在的诊断难题。其非特异性特征可能包括原因不明的发热、肝脾肿大、淋巴结病、脑膜炎和各种血液学异常，即贫血、全血细胞减少和类白血病反应。结核是与骨髓纤维化相关的非造血系统疾病之一。在此，我们报告一例伴有巨大脾肿大、严重全血细胞减少和骨髓纤维化的播散性结核病例。
