Shahid Beheshti University of Medical Science, Tehran, Iran.
Iran University of Medical Science, Tehran, Iran.
J Med Case Rep. 2021 Nov 8;15(1):550. doi: 10.1186/s13256-021-03038-3.
Primary myelofibrosis is a rare myeloproliferative disorder in middle-aged and old adults and should be distinguished from secondary and reactive causes of bone marrow fibrosis because, in reactive fibrosis, treatment approaches depend on the underlying etiology.
Here we report the case of a middle-aged Iranian man who was diagnosed and treated as primary myelofibrosis at presentation, and whose final diagnosis was disseminated tuberculosis with reactive bone marrow fibrosis.
It is prudent to evaluate the potential causes of myelofibrosis in any patient with the diagnosis primary myelofibrosis. Tuberculosis can be an important etiology of bone marrow fibrosis, especially in endemic areas.
原发性骨髓纤维化是一种罕见的中老年人骨髓增殖性疾病，应与骨髓纤维化的继发性和反应性原因相区别，因为在反应性纤维化中，治疗方法取决于潜在的病因。
在这里，我们报告了一个中年伊朗男性的病例，他在就诊时被诊断为原发性骨髓纤维化并接受治疗，最终诊断为播散性肺结核伴反应性骨髓纤维化。
对于任何被诊断为原发性骨髓纤维化的患者，评估骨髓纤维化的潜在原因是谨慎的。结核病可能是骨髓纤维化的一个重要病因，尤其是在流行地区。
