Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan.
Department of Pathology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan.
Int J Colorectal Dis. 2020 Sep;35(9):1801-1805. doi: 10.1007/s00384-020-03631-w. Epub 2020 May 30.
Myenteric ganglionitis is a disorder that causes intestinal motor dysfunction. It may be caused due to neoplastic, central nervous system, or systemic infectious disorders. However, some cases are considered to be idiopathic in origin.
A 33-year-old man was admitted to the hospital with sudden severe abdominal pain accompanied by watery diarrhea. Computed tomography imaging revealed edema of the entire small intestinal wall without ischemic changes. Detailed examination could not be performed for identifying the cause of abdominal pain because of the patient's worsened general condition, and he died 7 days after onset. The autopsy results confirmed the cause of the patient's severe abdominal pain as an idiopathic myenteric ganglionitis.
Some patients with idiopathic myenteric ganglionitis might die without a definitive diagnosis during their lifetime because of the rarity of this disease. When encountering severe intestinal motility abnormalities of unknown cause, physicians should consider idiopathic myenteric ganglionitis when choosing therapy.
肌间神经节炎是一种导致肠道运动功能障碍的疾病。它可能由肿瘤、中枢神经系统或全身性感染性疾病引起。然而，有些病例被认为是原发性的。
一名 33 岁男性因突发剧烈腹痛伴水样腹泻而入院。计算机断层扫描成像显示整个小肠壁水肿，无缺血改变。由于患者一般情况恶化，详细检查无法进行以确定腹痛的原因，他在发病后 7 天死亡。尸检结果证实患者的严重腹痛的原因为特发性肌间神经节炎。
由于这种疾病罕见，一些特发性肌间神经节炎患者在有生之年可能无法得到明确诊断而死亡。当遇到原因不明的严重肠道运动功能障碍时，医生在选择治疗方法时应考虑特发性肌间神经节炎。
