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COVID-19 相关高凝状态下的急性肺栓塞。

Acute pulmonary embolism in COVID-19 related hypercoagulability.

机构信息

General Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padua, Italy.

出版信息

J Thromb Thrombolysis. 2020 Jul;50(1):223-226. doi: 10.1007/s11239-020-02160-1.

Abstract

Since December 2019, a novel Coronavirus (SARS-CoV-2) was confirmed as the etiologic agent of a worldwide outbreak of a pneumonia that can result in severe respiratory failure. This clinical entity seems to be associated with a marked hypercoagulable state that causes both arterial and venous thromboembolic complications. Therefore, an adequate anti-thrombotic prophylaxis is recommended in hospitalized COVID-19 patients. Although rapidly worsening respiratory symptoms in a patient with SARS-CoV-2 respiratory infection may correlate with worsening pneumonia itself, it may also mask a pulmonary embolism. We report the case of a 50-year-old man affected by SARS-CoV-2 pneumonia, who developed acute pulmonary embolism.

摘要

自 2019 年 12 月以来,一种新型冠状病毒(SARS-CoV-2)已被确认为导致全球范围内肺炎爆发的病原体,这种肺炎可导致严重的呼吸衰竭。这种临床病症似乎与明显的高凝状态有关,可导致动脉和静脉血栓栓塞并发症。因此,建议对住院的 COVID-19 患者进行适当的抗血栓预防。尽管 SARS-CoV-2 呼吸道感染患者的呼吸症状迅速恶化可能与肺炎本身的恶化相关,但它也可能掩盖肺栓塞。我们报告了一例 50 岁男性 SARS-CoV-2 肺炎患者,该患者发生了急性肺栓塞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33a5/7260472/823baa1239a7/11239_2020_2160_Fig1_HTML.jpg

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