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Early Detection of Huntington Disease.亨廷顿病的早期检测
Future Neurol. 2010 Jan;5(1). doi: 10.2217/fnl.09.78.
5
The dillman total design survey method.迪尔曼总设计调查法。
Can Fam Physician. 1986 Nov;32:2366-8.
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"Frontal" behaviors before the diagnosis of Huntington's disease and their relationship to markers of disease progression: evidence of early lack of awareness.亨廷顿病诊断前的“额叶”行为及其与疾病进展标志物的关系:早期缺乏意识的证据。
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Validation of self-report depression rating scales in Huntington's disease.在亨廷顿病中自我报告抑郁评定量表的验证。
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8
Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.亨廷顿舞蹈病纵向TRACK-HD研究中的生物学和临床表现:基线数据的横断面分析
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9
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10
Engagement with genetic discrimination: concerns and experiences in the context of Huntington disease.应对基因歧视:亨廷顿舞蹈症背景下的担忧与经历
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亨廷顿病患者的控制点:一项横断面研究。

Locus of control in patients with Huntington disease: a cross-sectional study.

作者信息

Stainsby Brynne E, Mior Silvano, Guttman Mark

机构信息

Canadian Memorial Chiropractic College, Toronto, Ontario, Canada.

Center for Movement Disorders, Toronto, Ontario, Canada.

出版信息

J Can Chiropr Assoc. 2020 Apr;64(1):65-75.

PMID:32476669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7250512/
Abstract

BACKGROUND

Health locus of control (LOC) represents an individual's beliefs regarding one's ability to influence health outcomes. In patients with chronic and neurodegenerative diseases, greater internal LOC has been associated with lower levels of disability.

OBJECTIVE

To examine LOC in patients with Huntington disease (HD).

METHODS

A cross-sectional study of individuals affected by HD, stratified by disease status, was conducted. Participants completed a demographic questionnaire, the Internal Control Index (ICI), and the Hospital Anxiety and Depression Scales.

RESULTS

Thirty-four subjects completed the study. All groups demonstrated greater internal LOC (measured by ICI scores), and significant differences between groups were observed. Secondary analysis demonstrated relationships between depressive symptoms and anxiety symptoms, and ICI score and time from clinical diagnosis of HD.

CONCLUSION

As patients with chronic pain and neurodegenerative diseases such as HD are likely to present for chiropractic care, identifying factors such as anxiety, depression and LOC may affect patients' response to care.

摘要

背景

健康控制点(LOC)代表个人对自身影响健康结果能力的信念。在慢性和神经退行性疾病患者中,更强的内控点与更低的残疾水平相关。

目的

研究亨廷顿舞蹈病(HD)患者的健康控制点。

方法

对受HD影响的个体进行了一项横断面研究,按疾病状态分层。参与者完成了一份人口统计学问卷、内部控制指数(ICI)以及医院焦虑抑郁量表。

结果

34名受试者完成了研究。所有组均表现出更强的内控点(通过ICI评分衡量),且组间观察到显著差异。二次分析表明抑郁症状与焦虑症状之间以及ICI评分与HD临床诊断后的时间之间存在关联。

结论

由于患有慢性疼痛和神经退行性疾病(如HD)的患者可能会寻求整脊治疗,识别焦虑、抑郁和健康控制点等因素可能会影响患者对治疗的反应。