Vargas Jose, Le Phuc, Shahedi Maysam, Gahan Jeffrey, Johnson Brett, Dormer James D, Shahub Sarah, Pfefferle Matthew, Judson Blake O, Alshara Yasmeen, Li Qinmei, Fei Baowei
Department of Bioengineering, The Univ. of Texas at Dallas, TX.
Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX.
Proc SPIE Int Soc Opt Eng. 2020 Feb;11319. doi: 10.1117/12.2549892. Epub 2020 Mar 16.
We developed a reliable and repeatable process to create hyper-realistic, kidney phantoms with tunable image visibility under ultrasound (US) and CT imaging modalities. A methodology was defined to create phantoms that could be produced for renal biopsy evaluation. The final complex kidney phantom was devised containing critical structures of a kidney: kidney cortex, medulla, and ureter. Simultaneously, some lesions were integrated into the phantom to mimic the presence of tumors during biopsy. The phantoms were created and scanned by ultrasound and CT scanners to verify the visibility of the complex internal structures and to observe the interactions between material properties. The result was a successful advancement in knowledge of materials with ideal acoustic and impedance properties to replicate human organs for the field of image-guided interventions.
我们开发了一种可靠且可重复的流程，以创建在超声（US）和CT成像模式下具有可调图像可见性的超逼真肾脏模型。定义了一种方法来创建可用于肾活检评估的模型。设计了最终的复杂肾脏模型，其中包含肾脏的关键结构：肾皮质、髓质和输尿管。同时，将一些病变整合到模型中，以模拟活检期间肿瘤的存在。通过超声和CT扫描仪对模型进行创建和扫描，以验证复杂内部结构的可见性，并观察材料特性之间的相互作用。结果是在具有理想声学和阻抗特性的材料知识方面取得了成功进展，以便为图像引导介入领域复制人体器官。
