Naz Ilknur, Sahin Hulya, Demirci Uçsular Fatma, Yalnız Enver
Katip Celebi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Izmir, Turkey.
Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey.
Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(4):299-307. doi: 10.36141/svdld.v35i4.6830. Epub 2020 Mar 9.
Exercise training have been shown to be the effective approach for functional outcomes in interstitial lung diseases (ILD). In many studies, the duration of exercise programs (EPs) varies between 8-12 weeks. However, the optimal duration of EPs is still unknown. In our prospective non-controlled study, we aimed to compare the results of the 8 week with the results of the 12 week of the PR programs applied to the patients with ILD. A total of 14 patients [Age; 63(53,70) years, body mass index: 28(25,32) kg/m, disease duration; 1.5 (1,4) years] with ILD [11 idiopathic pulmonary fibrosis, 2 sarcoidosis (stage 3 and 4) and 1 nonspecific interstitial pneumonia] were included in the study. 6-minute walk test, pulmonary function test, arterial blood gas analysis, mMRC dyspnea scale, quality of life questionnaires and hospital anxiety depression scale were performed at before and 8 and 12 weeks after the program. 6-minute walk distance, dyspnea, anxiety, depression and quality of life improved both at 8 and 12 week after EP when compared the with the initial assessment(<0.05). When compared with 8 week; mMRC dyspnea score, 6-minute walk distance and quality of life scores significantly improved at 12 weeks (=0.046, =0.016, <0.05, respectively). Prolonging duration of the EPs results in more improvement in functional outcomes in patients with ILD. However, it has no effect on pulmonary functions and arterial blood gas results. .
运动训练已被证明是改善间质性肺疾病（ILD）功能结局的有效方法。在许多研究中，运动计划（EP）的持续时间在8至12周之间。然而，EP的最佳持续时间仍然未知。在我们的前瞻性非对照研究中，我们旨在比较应用于ILD患者的8周PR计划与12周PR计划的结果。共有14例ILD患者[年龄：63（53，70）岁，体重指数：28（25，32）kg/m²，病程；1.5（1，4）年][11例特发性肺纤维化，2例结节病（3期和4期）和1例非特异性间质性肺炎]纳入研究。在计划前以及计划后的8周和12周进行6分钟步行试验、肺功能测试、动脉血气分析、mMRC呼吸困难量表、生活质量问卷和医院焦虑抑郁量表。与初始评估相比，EP后8周和12周时6分钟步行距离、呼吸困难、焦虑、抑郁和生活质量均有所改善（<0.05）。与8周相比；12周时mMRC呼吸困难评分、6分钟步行距离和生活质量评分显著改善（分别为=0.046，=0.016，<0.05）。延长EP的持续时间可使ILD患者的功能结局得到更大改善。然而，它对肺功能和动脉血气结果没有影响。
