Özmen İpek, Yıldırım Elif, Karakış Meral, Öztürk Murat, Aydın Rüya, Şahal Emre
Department of pulmonology and Pulmonary rehabilitation unit, University of Health Sciences Süreyyapaşa Chest Diseases and Thoracic Surgery Research and Training Hospital, İstanbul Türkiye.
1Department of pulmonology and Pulmonary rehabilitation unit, University of Health Sciences Süreyyapaşa Chest Diseases and Thoracic Surgery Research and Training Hospital, İstanbul Türkiye.
Sarcoidosis Vasc Diffuse Lung Dis. 2024 Sep 24;41(3):e2024038. doi: 10.36141/svdld.v41i3.15530.
In addition to dyspnoea and cough in interstitial lung diseases (ILD), the main symptom is decreased effort capacity. Pulmonary rehabilitation (PR)is recommended besides medical treatment approaches in chronic respiratory diseases. PR programs include approaches such as exercise training, patient and family training, nutritional assessment and support, psychosocial assessment and support. COPD patients more often directed to PR programs, besides that PR is also recommended for ILD. In this study, we aimed to evaluate the PR-related gains in patinets with IPF and non-IPF ILD.
This retrospective study that we evaluated the PR data, demographic features of the patients with ILD who completed PR program between 2017 and 2020. PR was an 8-week (2days) outpatient PR program including aerobic and strengthening exercises. The 6-minute walking test (6MWT) results, quality of life scores that were recorded at the beginning and end of the PR program were evaluated.The patients were evaluated in two groups, patinets with IPF and non-IPF ILD.
A total of 56 patients (30 IPF, 26 non-IPF) with mean age 62±10 were included in the study. Among IPF patients 23 (77%) of them were receiving antifibrotic drugs. Non -IPF patients were: Unclassified ILD 9(16%), nonspecific interstitial pneumonia (NSIP) 8 (14%), sarcoidosis 3(%5), fibrotic hypersensitivity pneumonitis (fHP) 3 (5%), sjogren 2 (4%), scleroderma 1(2%). Both in IPF and non-IPF groups improvement in 6MWT, SGRQ total score after PR were statistically significantly improved (p= 0.001, p=0.002), (p= 0.001, p=0.018). Inspiratory muscle evaluation, MIP statistically increased after PR both in IPF and non-IPF patients (p= 0.015, p=0.028). There no significant differences in gains after PR program in walking capacity, quality of life, maximum inspiratory pressure between IPF and non-IPF patients.
PR programs provide significant gains both in patints with IPF and non-IPF ILD. It is important that patients should be directed to PR programs in the early stages of ILD.
除间质性肺疾病（ILD）中的呼吸困难和咳嗽外，主要症状是运动能力下降。除了慢性呼吸道疾病的药物治疗方法外，还推荐进行肺康复（PR）。PR计划包括运动训练、患者及家属培训、营养评估与支持、心理社会评估与支持等方法。慢性阻塞性肺疾病（COPD）患者更常接受PR计划，此外PR也推荐用于ILD。在本研究中，我们旨在评估特发性肺纤维化（IPF）和非IPF-ILD患者与PR相关的获益。
这是一项回顾性研究，我们评估了2017年至2020年间完成PR计划的ILD患者的PR数据和人口统计学特征。PR是一项为期8周（2天）的门诊PR计划，包括有氧运动和强化运动。评估了PR计划开始和结束时记录的6分钟步行试验（6MWT）结果、生活质量评分。患者分为两组，IPF患者和非IPF-ILD患者。
共有56例患者（30例IPF，26例非IPF）纳入研究，平均年龄62±10岁。在IPF患者中，23例（77%）正在接受抗纤维化药物治疗。非IPF患者包括：未分类的ILD 9例（16%）、非特异性间质性肺炎（NSIP）8例（14%）、结节病3例（5%）、纤维化性过敏性肺炎（fHP）3例（5%）、干燥综合征2例（4%）、硬皮病1例（2%）。在IPF组和非IPF组中，PR后6MWT、圣乔治呼吸问卷（SGRQ）总分均有统计学显著改善（p = 0.001，p = 0.002），（p = 0.001，p = 0.018）。IPF组和非IPF组患者PR后吸气肌评估、最大吸气压（MIP）均有统计学显著增加（p = 0.015，p = 0.028）。IPF组和非IPF组患者PR计划后的步行能力、生活质量、最大吸气压获益无显著差异。
PR计划在IPF和非IPF-ILD患者中均能带来显著获益。在ILD早期将患者导向PR计划很重要。
