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土耳其社区居住老年人中精神活性药物的使用与跌倒情况

Psychoactive drug use and falls among community-dwelling Turkish older people.

作者信息

Naharci Mehmet Ilkin, Oguz Ekin Oktay, Celebi Fatih, Oguz Senay Ozgun, Yilmaz Osman, Tasci Ilker

机构信息

Department of Geriatrics, University of Health Sciences, Gulhane Training and Research Hospital, Ankara, Turkey.

Department of Home Health Services, Gulhane Training and Research Hospital, Ankara, Turkey.

出版信息

North Clin Istanb. 2019 Jul 10;7(3):260-266. doi: 10.14744/nci.2019.30316. eCollection 2020.

Abstract

OBJECTIVE

Data on the relationship between fall and psychoactive drug use among Turkish older people are limited. This study aims to investigate the prevalence of falls and the associations between psychoactive drug use and falls in community-dwelling Turkish older people.

METHODS

This single center study was performed using the medical records of subjects aged over 65 years admitted to the geriatric care unit. Demographic and lifestyle factors, clinical characteristics, medications, and data on mood, cognitive status, and functional performance were obtained from the comprehensive geriatric assessment records. Based on a fall history in the last 12 months, subjects were grouped as fallers and non-fallers. Subjects treated with a psychoactive drug were identified.

RESULTS

Among the total of 429 subjects, there were 184 (42.9%) fallers and 245 (57.1%) non-fallers. Of those, 33.3% were on psychoactive drug treatment. The proportion of psychoactive drug users was higher in the fallers group compared to non-fallers (45.1% vs. 24.5%, p<0.001). Multivariable logistic regression analysis showed age ≥75 years (OR=1.83;CI: 1.09-3.09; p=0.023), female gender (OR=2.70;CI: 1.6-4.50; p<0.001), and psychoactive drug use (OR=2.14;CI 1.32-3.48; p=0.002) as independent predictors of falls.

CONCLUSION

We found that about one-third of geriatric outpatients were on psychoactive drug treatment in Turkey that was independently associated with the risk of falls.

摘要

目的

关于土耳其老年人跌倒与使用精神活性药物之间关系的数据有限。本研究旨在调查社区居住的土耳其老年人中跌倒的患病率以及精神活性药物使用与跌倒之间的关联。

方法

本单中心研究使用了老年护理病房收治的65岁以上受试者的病历。从综合老年评估记录中获取人口统计学和生活方式因素、临床特征、用药情况以及情绪、认知状态和功能表现的数据。根据过去12个月的跌倒史,将受试者分为跌倒者和非跌倒者。确定接受精神活性药物治疗的受试者。

结果

在总共429名受试者中,有184名(42.9%)跌倒者和245名(57.1%)非跌倒者。其中,33.3%接受精神活性药物治疗。跌倒者组中精神活性药物使用者的比例高于非跌倒者(45.1%对24.5%,p<0.001)。多变量逻辑回归分析显示,年龄≥75岁(OR=1.83;CI:1.09 - 3.09;p=0.023)、女性(OR=2.70;CI:1.6 - 4.50;p<0.001)和使用精神活性药物(OR=2.14;CI 1.32 - 3.48;p=0.002)是跌倒的独立预测因素。

结论

我们发现,在土耳其,约三分之一的老年门诊患者接受精神活性药物治疗,这与跌倒风险独立相关。

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Aging Clin Exp Res. 2018 Nov;30(11):1345-1351. doi: 10.1007/s40520-018-0950-9. Epub 2018 Apr 17.

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