Mansoor Kanaan, De Souza Goncalves Bruno, Lakhani Hari Vishal, Tashani Mohammad, Jones Sharon E, Sodhi Komal, Thompson Ellen, Dougherty Thomas
Cardiology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Surgery, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Cureus. 2023 Mar 21;15(3):e36468. doi: 10.7759/cureus.36468. eCollection 2023 Mar.
Substance abuse poses considerable clinical, economic, and social challenges. West Virginia is hailed as the epicenter of the substance abuse in the United States, the prevalence and pattern of different trauma mechanisms in a rural context or in patients with different forms of substance abuse remain unclear.
We performed the following analysis to understand the prevalence of substance abuse in patients with different trauma mechanisms in the rural setting with high substance abuse in the West Virginia.
We performed a cross-sectional retrospective analysis of adult trauma patients (motor vehicle, fall, assault, firearm suicide, brawl/rape and machinery) hospitalized in two tertiary care hospitals in West Virginia between 2006 and 2016. We identified all patients who had a urine drug screen (UDS) test and extracted the data related to the substance and trauma.
Among 8734 patients screened using UDS, 5940 (68.1%) patients were tested positive for the substance. Opiates, alcohol, benzodiazepines, and cannabis were the four most common substances identified in trauma victims. In all instances, the prescribed drug was less than 20%. Fatal outcome was observed in 366 patients in the sample, with 44% (n=162) testing positive for UDS, 12% (n=45) testing positive for only alcohol, and 15% (n=56) testing positive for both alcohol and UDS. Regarding the trauma mechanism, the motor vehicle accident (MVA) was the most prominent with a clear association of substance abuse with fatal outcome.
The most prevalent trauma mechanism was a MVA, with a strong link between drug usage and mortality. Due to the high incidence of positive substance abuse screens, UDS tests may need to be more widely implemented in trauma in the West Virginia region. The findings of this study might help in establishing regional or national policies to reduce acute substance abuse.
药物滥用带来了相当大的临床、经济和社会挑战。西弗吉尼亚州被誉为美国药物滥用的中心,然而在农村地区或不同形式药物滥用患者中,不同创伤机制的患病率和模式仍不清楚。
我们进行了以下分析,以了解在西弗吉尼亚州药物滥用率高的农村地区,不同创伤机制患者中药物滥用的患病率。
我们对2006年至2016年间在西弗吉尼亚州两家三级护理医院住院的成年创伤患者(机动车事故、跌倒、袭击、枪支自杀、斗殴/强奸和机械事故)进行了横断面回顾性分析。我们确定了所有进行过尿液药物筛查(UDS)测试的患者,并提取了与药物和创伤相关的数据。
在8734名接受UDS筛查的患者中,5940名(68.1%)患者的药物检测呈阳性。阿片类药物、酒精、苯二氮卓类药物和大麻是在创伤受害者中发现的四种最常见药物。在所有情况下,处方药的比例不到20%。样本中有366名患者出现致命结局,其中44%(n = 162)的UDS检测呈阳性,12%(n = 45)仅酒精检测呈阳性,15%(n = 56)酒精和UDS检测均呈阳性。关于创伤机制,机动车事故(MVA)最为突出,药物滥用与致命结局之间存在明显关联。
最常见的创伤机制是MVA,药物使用与死亡率之间存在紧密联系。由于药物滥用筛查呈阳性的发生率很高,在西弗吉尼亚州地区的创伤治疗中可能需要更广泛地开展UDS测试。本研究结果可能有助于制定区域或国家政策以减少急性药物滥用。