Lindeberg S, Axelsson O, Jorner U, Malmberg L, Sandström B
Department of Obstetrics and Gynaecology, Orebro Medical Center Hospital, Sweden.
Acta Obstet Gynecol Scand. 1988;67(7):605-9. doi: 10.3109/00016348809004272.
Primiparas with hypertension first recognized in pregnancy and an age- and parity-matched control group, normotensive throughout pregnancy, were monitored during 5-6 years with blood pressure recordings performed in a standardized way. At the end of the study period, 21 out of 49 women with hypertension in pregnancy had developed hypertension requiring therapy or borderline hypertension, compared with 2 women in the control group who had developed borderline hypertension. Therapy was required in 7 of the women. Factors associated with increased risk of developing hypertension were gestational week at diagnosis of gestational hypertension, 1st diastolic blood pressure during follow-up, family history, smoking, and age.
首次在孕期被诊断为高血压的初产妇以及与之年龄和产次匹配、孕期血压一直正常的对照组,在5至6年期间接受监测,血压记录采用标准化方式进行。在研究期结束时,49名孕期高血压女性中有21人发展为需要治疗的高血压或临界高血压,而对照组中有2名女性发展为临界高血压。7名女性需要接受治疗。与高血压发病风险增加相关的因素包括妊娠高血压诊断时的孕周、随访期间首次舒张压、家族史、吸烟和年龄。