地塞米松诱导山羊血清生化指标变化
Dexamethasone-induced serum biochemical changes in goats.
作者信息
Maddux J M, Moore W E, Keeton K S, Shull R M
机构信息
Department of Pathobiology, University of Tennessee, Knoxville 37901.
出版信息
Am J Vet Res. 1988 Nov;49(11):1937-40.
PMID:3247919
Abstract
Dexamethasone was administered at sequential dosages of 0.1 mg/kg/day for 3 days and 1 mg/kg/day for 3 days to 6 adult female goats. The greatest effects induced were hypokalemia, hypophosphatemia, and hyperglycemia. At low dosages of dexamethasone, transient increases (P less than 0.05) developed in serum sodium and chloride concentrations. An effect on hepatic physiology or iron metabolism was not observed.
摘要
对6只成年雌性山羊连续3天给予地塞米松，剂量为0.1毫克/千克/天，随后3天剂量为1毫克/千克/天。所诱导的最大影响是低钾血症、低磷血症和高血糖。在低剂量地塞米松作用下，血清钠和氯浓度出现短暂升高（P<0.05）。未观察到对肝脏生理或铁代谢的影响。
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